Gfap Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gfap
glial fibrillary acidic protein
MGI:95697

29 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Del(9Hspb2-Cryab)1Wawr/Del(9Hspb2-Cryab)1Wawr Gfap^tm2Mes/Gfap⁺ involves: 129S4/SvJae * 129S7/SvEvBrd	normal mortality/aging	J:146191
Gfap^tm1Pkny/Gfap^tm1Pkny Ppt1^tm1Hof/Ppt1^tm1Hof Vim^tm1Cba/Vim^tm1Cba involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac * C57BL/6	abnormal brain morphology	J:177265
	abnormal cytokine level	J:177265
	abnormal nervous system morphology	J:177265
	abnormal visual cortex morphology	J:177265
	brain atrophy	J:177265
	brain inflammation	J:177265
	decreased brain weight	J:177265
	hippocampal neuron degeneration	J:177265
	neurodegeneration	J:177265
	premature death	J:177265
	thin cerebral cortex	J:177265
Gfap^tm1Pkny/Gfap^tm1Pkny Vim^tm1Cba/Vim^tm1Cba involves: 129/Sv * 129P2/OlaHsd * C57BL/6	abnormal dentate gyrus morphology	J:106195
	abnormal neuron differentiation	J:106195
Gfap^tm1Pkny/Gfap^tm1Pkny Vim^tm1Cba/Vim^tm1Cba involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal astrocyte morphology	J:125659
	abnormal astrocyte physiology	J:125659
	abnormal spinal cord morphology	J:124385
	astrocytosis	J:124385
	decreased inflammatory response	J:123278
	decreased neuron apoptosis	J:123278
	gliosis	J:123278
	increased vasodilation	J:124385
	intracranial hemorrhage	J:124385
	normal nervous system phenotype	J:124385
	normal vision/eye phenotype	J:123278
Gfap^tm2Mes/Gfap⁺ Tg(GFAP)10Mes/0 involves: 129S6/SvEvTac * 129S7/SvEvBrd * FVB/N	abnormal astrocyte morphology	J:114689
	premature death	J:114689
	seizures	J:114689
Gfap^tm2Mes/Gfap⁺ Tg(GFAP)10Mes/0 involves: 129S7/SvEvBrd * FVB/N	abnormal hippocampus morphology	J:146191
	premature death	J:146191
Gfap^tm2Mes/Gfap⁺ Tg(GFAP)10Mes/0 Tg(GFAP-CRYAB)141.6Mes/0 involves: 129S4/SvJae * 129S7/SvEvBrd * FVB/N	abnormal hippocampus morphology	J:146191
	normal mortality/aging	J:146191
Gfap^tm2Mes/Gfap⁺ Tg(GFAP-CRYAB)141.6Mes/0 involves: 129S7/SvEvBrd * FVB/N	abnormal cell physiology	J:146191
Gfap^tm4Ito/Gfap^tm4Ito Vim^tm1Cba/Vim^tm1Cba either: (involves: 129P2/OlaHsd * 129S2/SvPas) or (involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6)	abnormal astrocyte morphology	J:78341
	abnormal CNS glial cell morphology	J:78341

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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