Ghrhr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ghrhr
growth hormone releasing hormone receptor
MGI:95710

52 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ghrhr^lit/Ghrhr^lit C3.B6-Ghrhr^lit/J	abnormal bone mineral density	J:209717
	abnormal bone structure	J:209717
	abnormal insulin-like growth factor I level	J:209717
	decreased body weight	J:209717
	decreased bone mineral density of femur	J:209717
	decreased volumetric bone mineral density	J:209717
	short femur	J:209717
Ghrhr^lit/Ghrhr^lit C57BL/6J-Ghrhr^lit	abnormal frequency of paradoxical sleep	J:82887
	abnormal lactation	J:5647
	abnormal metabolism	J:81023
	abnormal postnatal growth	J:5710, J:81023
	abnormal skeleton development	J:5710
	abnormal sleep pattern	J:82887
	abnormal somatotroph morphology	J:7211
	absent somatotroph secretory granules	J:7211
	normal behavior/neurological phenotype	J:81023
	decreased bone mass	J:81023
	decreased circulating growth hormone level	J:3735
	decreased growth hormone level	J:5647
	decreased prolactin level	J:5647
	decreased somatotroph cell number	J:7211
	decreased somatotroph cell size	J:7211
	decreased somatotroph secretory granule number	J:7211
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:85381
	increased susceptibility to age related obesity	J:5647
	increased total body fat amount	J:3735
	obese	J:81023
	postnatal growth retardation	J:5647
	proportional dwarf	J:5710
	reduced male fertility	J:5647
	small pituitary gland	J:5647
Ghrhr^lit/Ghrhr^lit C57BL/6J-Ghrhr^lit/J	abnormal bone structure	J:209717
	abnormal glucose homeostasis	J:95779
	abnormal insulin-like growth factor I level	J:209717
	decreased body weight	J:95779, J:209717
	decreased bone mineral density	J:209717
	decreased bone mineral density of femur	J:209717
	decreased circulating glucose level	J:95779
	decreased circulating insulin-like growth factor I level	J:95779
	decreased lean body mass	J:95779
	increased bone mineral density	J:95779
	increased circulating insulin level	J:95779
	increased total body fat amount	J:95779
	short femur	J:95779, J:209717
	slow postnatal weight gain	J:95779
Ghrhr^{tm1.1(KOMP)Vlcg}/Ghrhr⁺ C57BL/6N-Ghrhr^{tm1.1(KOMP)Vlcg}/J	hyperactivity	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
Ghrhr^{tm1.1(KOMP)Vlcg}/Ghrhr^{tm1.1(KOMP)Vlcg} C57BL/6N-Ghrhr^{tm1.1(KOMP)Vlcg}/J	abnormal auditory brainstem response	J:211773
	abnormal bone structure	J:211773
	abnormal sleep behavior	J:211773
	decreased body length	J:211773
	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating glucose level	J:211773
	decreased heart weight	J:211773
	decreased lean body mass	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased vertical activity	J:211773
	hyperactivity	J:211773
	increased circulating triglyceride level	J:211773
	increased grip strength	J:211773
	increased total body fat amount	J:211773
	thrombocytopenia	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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