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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gja5
gap junction protein, alpha 5
MGI:95716
30 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Apoetm1Unc/Apoetm1Unc
Gja5tm1Mchn/Gja5tm1Mchn
Tg(TIE2-lacZ)182Sato/0
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		abnormal neutrophil physiology J:162224
alveolitis J:162224
normal cardiovascular system phenotype J:162224
increased susceptibility to atherosclerosis J:162224
Gja1tm3(Gja5)Kwi/Gja1+
involves: 129P2/OlaHsd * C57BL/6 		irregular heartbeat J:65112
ventricular premature beat J:65112
Gja1tm3(Gja5)Kwi/Gja1tm3(Gja5)Kwi
involves: 129P2/OlaHsd * C57BL/6 		abnormal ovarian follicle morphology J:65112
abnormal seminiferous tubule morphology J:65112
cardiac hypertrophy J:65112
decreased body weight J:65112
decreased ovulation rate J:65112
decreased testis weight J:65112
female infertility J:65112
male infertility J:65112
oligozoospermia J:65112
postnatal lethality, incomplete penetrance J:65112
ventricular premature beat J:65112
normal vision/eye phenotype J:65112
Gja4tm1Paul/Gja4tm1Paul
Gja5tm1Paul/Gja5tm1Paul
involves: 129S4/SvJae * C57BL/6 		abnormal spermatogenesis J:80178
abnormal testis morphology J:80178
blood vessel congestion J:80178
gastrointestinal hemorrhage J:80178
increased vasodilation J:80178
lethality throughout fetal growth and development, incomplete penetrance J:80178
lung hemorrhage J:80178
neonatal lethality, incomplete penetrance J:80178
postnatal lethality, complete penetrance J:80178
Gja5tm1(Gja7)Hvr/Gja5tm1(Gja7)Hvr
involves: 129S2/SvPas * C57BL/6 		abnormal heart electrocardiography waveform feature J:92018
prolonged P wave J:92018
prolonged QRS complex duration J:92018
Gja5tm1(Gja7)Hvr/Gja5tm1(Gja7)Hvr
involves: 129S2/SvPas * CD-1 		abnormal heart electrocardiography waveform feature J:92018
abnormal impulse conducting system conduction J:92018
prolonged P wave J:92018
prolonged QRS complex duration J:92018
Gja5tm1Lumi/Gja5+
Irx3tm1Hui/Irx3tm1Hui
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal impulse conducting system conduction J:175992
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory