Gjc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gjc1
gap junction protein, gamma 1
MGI:95718

40 phenotypes from 9 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gjc1^{tm1.1(Gjd2)Kwi}/Gjc1^{tm1.1(Gjd2)Kwi} Tg(Myh6-cre)2182Mds/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	abnormal atrioventricular cushion morphology	J:182927
	abnormal impulse conducting system conduction	J:182927
	atrioventricular block	J:182927
	congestive heart failure	J:182927
	decreased cardiac muscle contractility	J:182927
	decreased embryo size	J:182927
	decreased heart rate	J:182927
	dilated heart	J:182927
	embryonic growth retardation	J:182927
	embryonic lethality during organogenesis, complete penetrance	J:182927
	enlarged heart	J:182927
	pericardial effusion	J:182927
Gjc1^{tm1.1(Gjd2)Kwi}/Gjc1^{tm1.1(Gjd2)Kwi} Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * SJL	normal nervous system phenotype	J:182927
	normal vision/eye phenotype	J:182927
Gjc1^{tm1.1(KOMP)Vlcg}/Gjc1^{tm1.1(KOMP)Vlcg} C57BL/6N-Gjc1^{tm1.1(KOMP)Vlcg}/MbpMmucd	preweaning lethality, complete penetrance	J:211773
Gjc1^{tm1.1(KOMP)Vlcg}/Gjc1^{tm1.1(KOMP)Vlcg} C57BL/6N-Gjc1^{tm1.1(KOMP)Vlcg}/Ucd	abnormal embryo size	J:211773
	abnormal pericardium morphology	J:211773
	edema	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
Gjc1^tm1.1Kni/Gjc1^tm1.1Kni involves: 129S/SvEv * C57BL/6	abnormal heart development	J:63214
	abnormal heart looping	J:63214
	absent atrioventricular cushions	J:63214
	absent trabeculae carneae	J:63214
	decreased cardiac muscle contractility	J:63214
	decreased embryo size	J:63214
	embryonic growth arrest	J:63214
	embryonic lethality during organogenesis, complete penetrance	J:63214
	enlarged heart	J:63214
	heart block	J:63214
	increased apoptosis	J:63214
	small placenta	J:63214
Gjc1^tm1Kni/Gjc1^tm1Kni involves: 129S/SvEv * C57BL/6	abnormal heart development	J:63214
	abnormal heart looping	J:63214
	absent atrioventricular cushions	J:63214
	absent trabeculae carneae	J:63214
	decreased cardiac muscle contractility	J:63214
	decreased embryo size	J:63214
	embryonic growth arrest	J:63214
	embryonic lethality during organogenesis, complete penetrance	J:63214
	enlarged heart	J:63214
	heart block	J:63214
	increased apoptosis	J:63214
	small placenta	J:63214
Gjc1^tm1Kwi/Gjc1^tm1Kwi Tg(Myh6-icre/ERT2)#Wet/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal heart electrocardiography waveform feature	J:205110
	abnormal sinoatrial node conduction	J:205110
	normal cardiovascular system phenotype	J:205110
	embryonic lethality during organogenesis, complete penetrance	J:205110
	prolonged PQ interval	J:205110
Gjc1^tm1Kwi/Gjc1^tm1Weil Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6	abnormal eye electrophysiology	J:95984
Gjc1^tm1Weil/Gjc1^tm1Weil Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6	abnormal eye electrophysiology	J:95984
	abnormal eye physiology	J:95984
Gjc1^tm2.1Kni/Gjc1^tm2.1Kni Not Specified	decreased cardiac output	J:103078
	impaired hematopoiesis	J:103078
	increased embryonic neuroepithelium apoptosis	J:103078
	thin myocardium	J:103078
Gjc1^tm2Kni/Gjc1^tm2Kni Tg(ACTC1-cre)1Miwa/0 involves: C57BL/6 * DBA	abnormal impulse conducting system conduction	J:103078
	abnormal placenta vasculature	J:103078
	decreased cardiac output	J:103078
	embryonic lethality during organogenesis, complete penetrance	J:103078
	impaired hematopoiesis	J:103078
	increased embryonic neuroepithelium apoptosis	J:103078
	thin myocardium	J:103078
Tg(Myh6-Gja7)927Kaya/0 involves: C57BL/6J * SJL/J	abnormal myocardial fiber physiology	J:104791
Tg(Myh6-Gja7)927Kaya/0 involves: C57BL/6J * SJL/J	irregular heartbeat	J:104791

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