Gjb1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gjb1
gap junction protein, beta 1
MGI:95719

13 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gjb1^tm1Kwi/Y involves: 129S4/SvJae	abnormal axon morphology	J:40955
	abnormal myelination	J:40955
	abnormal nerve conduction	J:40955
	abnormal nervous system morphology	J:40955
	abnormal Schwann cell morphology	J:40955
	normal behavior/neurological phenotype	J:40955
	demyelination	J:40955
Gjb1^tm1Kwi/Y involves: 129S4/SvJae * C57BL/6	abnormal axon morphology	J:85828
	abnormal liver physiology	J:36146
	abnormal myelin sheath morphology	J:85828
	abnormal nervous system morphology	J:85828
	abnormal Schwann cell morphology	J:85828
	normal behavior/neurological phenotype	J:85828
	decreased body weight	J:36146
	demyelination	J:85828
	increased liver glycogen level	J:36146
	normal nervous system phenotype	J:36146
Gjb1^tm1Kwi/Gjb1⁺ involves: 129S4/SvJae * C57BL/6	abnormal myelin sheath morphology	J:85828
	abnormal nervous system morphology	J:85828
	abnormal Schwann cell morphology	J:85828
	demyelination	J:85828
Gjb1^tm1Kwi/Gjb1^tm1Kwi involves: 129S4/SvJae	abnormal axon morphology	J:40955
	abnormal myelination	J:40955
	abnormal nerve conduction	J:40955
	abnormal nervous system morphology	J:40955
	abnormal Schwann cell morphology	J:40955
	normal behavior/neurological phenotype	J:40955
	demyelination	J:40955
Gjb1^tm1Kwi/Gjb1^tm1Kwi involves: 129S4/SvJae * C57BL/6	abnormal axon morphology	J:85828
	abnormal liver morphology	J:36146
	abnormal myelin sheath morphology	J:85828
	abnormal nervous system morphology	J:85828
	abnormal Schwann cell morphology	J:85828
	normal behavior/neurological phenotype	J:85828
	decreased body weight	J:36146
	demyelination	J:85828
	normal nervous system phenotype	J:36146

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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