About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gjb1
gap junction protein, beta 1
MGI:95719
42 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Gja1tm2(Gjb1)Kwi/Gja1+
involves: 129P2/OlaHsd * C57BL/6 		abnormal mammary gland alveolus morphology J:65112
abnormal mammary gland luminal epithelium morphology J:65112
abnormal milk ejection J:65112
maternal effect J:65112
ventricular premature beat J:65112
Gja1tm2(Gjb1)Kwi/Gja1tm2(Gjb1)Kwi
involves: 129P2/OlaHsd * C57BL/6 		abnormal heart right ventricle morphology J:65112
abnormal heart ventricle morphology J:65112
abnormal ovarian follicle morphology J:65112
abnormal seminiferous tubule morphology J:65112
abnormal trabecula carnea morphology J:65112
cataract J:65112
decreased body weight J:65112
decreased ovulation rate J:65112
decreased testis weight J:65112
irregular heartbeat J:65112
male infertility J:65112
oligozoospermia J:65112
postnatal lethality, incomplete penetrance J:65112
reduced female fertility J:65112
thin ventricular wall J:65112
ventricular tachycardia J:65112
Gjb1tm1Kwi/Y
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal gait J:219594
abnormal oligodendrocyte apoptosis J:219594
abnormal oligodendrocyte morphology J:219594
astrocytosis J:219594
axon degeneration J:219594
demyelination J:219594
dysmyelination J:219594
impaired coordination J:219594
microgliosis J:219594
optic nerve inflammation J:219594
premature death J:219594
spinal cord inflammation J:219594
tonic seizures J:219594
tremors J:219594
Gjb1tm1Kwi/Y
Gjc2tm2.1Kwi/Gjc2tm2.1Kwi
involves: 129S4/SvJae * C57BL/6 * SJL 		abnormal motor capabilities/coordination/movement J:174197
abnormal myelination J:174197
astrocytosis J:174197
ataxia J:174197
premature death J:174197
Gjc2tm1(EGFP)Kwi/Gjc2tm1(EGFP)Kwi
Gjb1tm1Kwi/Gjb1tm1Kwi
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal gait J:219594
abnormal myelination J:83885
abnormal oligodendrocyte apoptosis J:219594
abnormal oligodendrocyte morphology J:219594
astrocytosis J:219594
axon degeneration J:219594
demyelination J:219594
dysmyelination J:219594
impaired coordination J:219594
microgliosis J:219594
neurodegeneration J:83885
optic nerve inflammation J:219594
premature death J:83885, J:219594
seizures J:83885
spinal cord inflammation J:219594
sporadic seizures J:83885
tonic seizures J:83885, J:219594
tremors J:83885, J:219594
Gjc2tm1Paul/Gjc2tm1Paul
Gjb1tm1Kwi/Gjb1tm1Kwi
involves: 129/Sv * C57BL/6 		abnormal myelination J:84338
absent optic nerve J:84338
demyelination J:84338
premature death J:84338
tonic seizures J:84338
tremors J:84338
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory