Glul Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Glul
glutamate-ammonia ligase
MGI:95739

37 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Glul^tm1.1Geno/Glul^tm1.1Geno B6J.Cg-Glul^tm1.1Geno	no abnormal phenotype detected	J:221031
Glul^tm1.1Geno/Glul^tm1.1Geno Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * C57BL/6J * DBA	abnormal fear-related response	J:221031
	normal homeostasis/metabolism phenotype	J:221031
	hyperactivity	J:221031
	increased circulating ammonia level	J:221031
	normal liver/biliary system phenotype	J:221031
	oxidative stress	J:221031
	premature death	J:221031
Glul^tm1.1Ncd/Glul^tm1.1Ncd Emx1^tm1(cre)Krj/Emx1⁺ B6.Cg-Glul^tm1.1Ncd Emx1^tm1(cre)Krj	abnormal blood vessel physiology	J:272643
	abnormal brain vasculature morphology	J:272643
	abnormal locomotor activation	J:272643
	astrocytosis	J:272643
	decreased anxiety-related response	J:272643
	decreased aspartic acid level	J:272643
	decreased gamma-aminobutyric acid level	J:272643
	decreased glutamic acid level	J:272643
	decreased glutamine level	J:272643
	decreased locomotor activity	J:272643
	decreased vertical activity	J:272643
	hippocampus pyramidal cell degeneration	J:272643
	increased locomotor activity	J:272643
	neurodegeneration	J:272643
	premature death	J:272643
	seizures	J:272643
Glul^tm1Whla/Glul^tm1Whla FVBHanHsd.129P2-Glul^tm1Whla	embryonic lethality before implantation, incomplete penetrance	J:122377
Glul^tm1Whla/Glul^tm1Whla FVBHanHsd.129P2-Glul^tm1Whla	embryonic lethality, complete penetrance	J:122377
Glul^tm1Whla/Glul^tm2Whla involves: 129P2/OlaHsd	embryonic lethality between somite formation and embryo turning, complete penetrance	J:122377
Glul^tm3Whla/Glul^tm1Whla Tg(Ckmm-cre)5Khn/0 involves: 129P2/OlaHsd * FVB	abnormal amino acid level	J:161082
	abnormal ammonia homeostasis	J:161082
	abnormal postnatal growth	J:161082
	decreased circulating glutamine level	J:161082
	decreased glutamine level	J:161082
Glul^tm3Whla/Glul^tm1Whla Tg(GFAP-cre)25Mes/0 involves: 129P2/OlaHsd * FVB/N	abnormal ammonia homeostasis	J:162067
	abnormal brain morphology	J:162067
	abnormal food intake	J:162067
	decreased alanine level	J:162067
	decreased circulating glucose level	J:162067
	decreased glutamine level	J:162067
	increased glycine level	J:162067
	postnatal lethality, complete penetrance	J:162067
Glul^tm3Whla/Glul^tm3Whla Tg(Ckmm-cre)5Khn/0 involves: 129P2/OlaHsd * FVB	abnormal amino acid level	J:161082
	abnormal ion homeostasis	J:161082
	abnormal postnatal growth	J:161082
Glul^tm3Whla/Glul^tm3Whla Tg(GFAP-cre)25Mes/0 involves: 129P2/OlaHsd * FVB/N	abnormal ammonia homeostasis	J:162067
	abnormal brain morphology	J:162067
	abnormal food intake	J:162067
	decreased alanine level	J:162067
	decreased circulating glucose level	J:162067
	decreased glutamine level	J:162067
	increased glycine level	J:162067
	postnatal lethality, complete penetrance	J:162067

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