Slc2a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
MGI:95755

32 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc2a1^em1Mase/Slc2a1^em1Mase involves: C57BL/6N	postnatal lethality, complete penetrance	J:308608
Slc2a1^Rgsc200/Slc2a1⁺ B6(D2)-Slc2a1^Rgsc200	abnormal brain wave pattern	J:281292
	abnormal circadian sleep/wake cycle	J:281292
	abnormal enzyme/coenzyme activity	J:281292
	abnormal glucose homeostasis	J:281292
	abnormal non-rapid eye movement sleep pattern	J:281292
	decreased body weight	J:281292
	decreased cellular glucose uptake	J:281292
	decreased cerebrospinal fluid glucose level	J:281292
	normal embryo phenotype	J:281292
	impaired contextual conditioning behavior	J:281292
	increased locomotor activity	J:281292
	normal nervous system phenotype	J:281292
	sporadic seizures	J:281292
Slc2a1^Rgsc200/Slc2a1⁺ C3.B6(D2)-Slc2a1^Rgsc200	behavioral arrest	J:281292
Slc2a1^Rgsc200/Slc2a1⁺ involves: C3H/HeJJcl * C57BL/6JJcl * DBA/2JJcl	behavioral arrest	J:281292
Slc2a1^Rgsc200/Slc2a1⁺ involves: C57BL/6JJcl * DBA/2JJcl	abnormal posture	J:281292
	ataxia	J:133634, J:281292
	behavioral arrest	J:133634, J:281292
	convulsive seizures	J:281292
	environmentally induced seizures	J:281292
	impaired passive avoidance behavior	J:133634
	slow movement	J:281292
Slc2a1^Rgsc200/Slc2a1^Rgsc200 B6(D2)-Slc2a1^Rgsc200	abnormal embryo development	J:281292
	abnormal embryo morphology	J:281292
	lethality throughout fetal growth and development, complete penetrance	J:281292
Slc2a1^tm1Dcdv/Slc2a1⁺ involves: 129S6/SvEvTac * C57BL/6J	abnormal motor capabilities/coordination/movement	J:108250
	decreased brain weight	J:108250
	decreased cellular glucose uptake	J:108250
	decreased cerebrospinal fluid glucose level	J:108250
	impaired coordination	J:108250
	sporadic seizures	J:108250
Slc2a1^tm1Dcdv/Slc2a1^tm1Dcdv involves: 129S6/SvEvTac * C57BL/6J	abnormal rostral-caudal axis patterning	J:108250
	anophthalmia	J:108250
	decreased embryo size	J:108250
	embryonic growth retardation	J:108250
	embryonic lethality during organogenesis, complete penetrance	J:108250

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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