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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
MGI:95760
36 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc6a9tm1.1Blt/Slc6a9+
C57BL/6J-Slc6a9tm1.1Blt 		normal behavior/neurological phenotype J:93288
enhanced NMDA-mediated synaptic currents J:93288
normal nervous system phenotype J:93288
Slc6a9tm1.1Blt/Slc6a9tm1.1Blt
C57BL/6J-Slc6a9tm1.1Blt 		prenatal lethality, complete penetrance J:93288
Slc6a9tm1.1Bois/Slc6a9tm1.1Bois
Tg(Camk2a-cre)2834Lusc/0
involves: C57BL/6J 		abnormal active avoidance behavior J:106967
abnormal conditioned taste aversion behavior J:106967
abnormal cued conditioning behavior J:106967
abnormal latent inhibition of conditioning behavior J:106967
enhanced NMDA-mediated synaptic currents J:106967
impaired behavioral response to addictive substance J:106967
Slc6a9tm1Betz/Slc6a9tm1Betz
involves: 129P2/OlaHsd * C57BL/6 		abnormal breathing pattern J:86624
abnormal inhibitory postsynaptic currents J:86624
abnormal limb posture J:86624
abnormal nervous system electrophysiology J:86624
abnormal nervous system physiology J:86624
abnormal suckling behavior J:86624
absent gastric milk in neonates J:86624
apnea J:86624
bradykinesia J:86624
decreased body weight J:86624
decreased pulmonary respiratory rate J:86624
dehydration J:86624
hyporesponsive to tactile stimuli J:86624
hypotonia J:86624
lethargy J:86624
neonatal lethality, complete penetrance J:86624
normal nervous system phenotype J:86624
respiratory distress J:86624
Slc6a9tm1Dgen/Slc6a9+
involves: 129P2/OlaHsd * C57BL/6 		increased body weight J:101679
Slc6a9tm1Dgen/Slc6a9tm1Dgen
involves: 129P2/OlaHsd * C57BL/6 		preweaning lethality, complete penetrance J:101679
Slc6a9tm1Jtc/Slc6a9+
involves: 129S6/SvEvTac * 129X1/SvJ 		abnormal nervous system physiology J:90689
abnormal NMDA-mediated synaptic currents J:90689
abnormal sensorimotor gating J:90689
abnormal spatial learning J:90689
Slc6a9tm1Jtc/Slc6a9tm1Jtc
involves: 129S6/SvEvTac * 129X1/SvJ 		abnormal nervous system physiology J:90689
neonatal lethality, complete penetrance J:90689
Slc6a9tm1Veul/Slc6a9tm1Veul
involves: 129P2/OlaHsd 		no abnormal phenotype detected J:161993
Slc6a9tm1Veul/Slc6a9tm1Veul
Tg(EIIa-cre)C5379Lmgd/?
involves: 129P2/OlaHsd * FVB/N 		abnormal motor capabilities/coordination/movement J:161993
hypotonia J:161993
neonatal lethality, complete penetrance J:161993
Slc6a9tm1Veul/Slc6a9tm1Veul
Tg(Gfap-cre)2Brn/?
involves: 129P2/OlaHsd * FVB/N 		hypotonia J:161993
postnatal lethality, incomplete penetrance J:161993
Slc6a9tm1Veul/Slc6a9tm1Veul
Tg(Syn1-cre)671Jxm/?
involves: 129P2/OlaHsd * C57BL/6 * CBA 		abnormal neuron physiology J:161993
normal behavior/neurological phenotype J:161993
normal muscle phenotype J:161993
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory