Gna13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gna13
guanine nucleotide binding protein, alpha 13
MGI:95768

22 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gna13^{tm1b(KOMP)Wtsi}/Gna13^{tm1b(KOMP)Wtsi} C57BL/6N-Gna13^{tm1b(KOMP)Wtsi}/Bay	abnormal embryo size	J:211773
	abnormal visceral yolk sac morphology	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Gna13^tm1Soff/Gna13^tm1Soff involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * SJL	abnormal vitelline vasculature morphology	J:99731
	embryonic growth retardation	J:99731
	embryonic lethality during organogenesis, complete penetrance	J:99731
	enlarged pericardium	J:99731
	excessive folding of visceral yolk sac	J:99731
	hemorrhage	J:99731
	pallor	J:99731
Gna13^tm1Soff/Gna13^tm1Soff involves: 129S1/Sv * C57BL/6J	abnormal angiogenesis	J:50566
	abnormal blood vessel morphology	J:50566
	abnormal extraembryonic tissue morphology	J:50566
	absent vitelline blood vessels	J:50566
	embryonic lethality during organogenesis, complete penetrance	J:50566
	pale yolk sac	J:50566
Gna13^tm1Soff/Gna13^tm2Cgh Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129S4/SvJae * C57BL/6 * SJL	abnormal vitelline vasculature morphology	J:99731
	embryonic growth retardation	J:99731
	embryonic lethality during organogenesis, incomplete penetrance	J:99731
	enlarged pericardium	J:99731
	excessive folding of visceral yolk sac	J:99731
	hemorrhage	J:99731
	pallor	J:99731
Gna13^tm2.1Cgh/Gna13^tm2.1Cgh involves: 129S4/SvJae * C57BL/6	embryonic lethality during organogenesis, complete penetrance	J:99731
Gna13^tm2.1Soff/Gna13^tm2.1Soff Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA * FVB/N	abnormal blood coagulation	J:99597
	abnormal platelet physiology	J:99597
	increased bleeding time	J:99597
Gna13^tm2.2Soff/Gna13^tm2.2Soff Tg(EIIa-cre)C5379Lmgd/? involves: FVB	abnormal blood coagulation	J:99597
	abnormal platelet physiology	J:99597
	increased bleeding time	J:99597
Gna13^tm2Cgh/Gna13^tm2Cgh Grhl3^tm1(cre)Cgh/Grhl3⁺ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * SJL	normal mortality/aging	J:157446
	normal nervous system phenotype	J:157446

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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