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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2)
MGI:95815
13 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Grik2tm1Bvis/Grik2tm1Bvis
129S/Sv-Grik2tm1Bvis 		abnormal CNS synaptic transmission J:107698
abnormal excitatory postsynaptic potential J:107698
abnormal long-term potentiation J:107698
abnormal single cell response J:107698
increased susceptibility to pharmacologically induced seizures J:107698
Grik2tm1Sfh/Grik2tm1Sfh
involves: 129S1/Sv 		abnormal CNS synaptic transmission J:148310
decreased paired-pulse facilitation J:148310
Grik2tm1Sfh/Grik2tm1Sfh
involves: 129S1/Sv * C57BL/6 		abnormal contextual conditioning behavior J:98109
abnormal cued conditioning behavior J:98109
abnormal glutamate-mediated receptor currents J:46932
abnormal long-term potentiation J:91763
decreased body weight J:46932
decreased fear-related response J:98109
decreased paired-pulse facilitation J:91763
decreased susceptibility to pharmacologically induced seizures J:46932
reduced long-term potentiation J:98109
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory