Gsn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gsn
gelsolin
MGI:95851

28 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gsn^tm1Djk/Gsn^tm1Djk either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	abnormal bone remodeling	J:60625
	abnormal immune system physiology	J:24346
	abnormal long bone diaphysis morphology	J:60625
	abnormal long bone epiphyseal plate morphology	J:60625
	abnormal osteoclast differentiation	J:60625
	abnormal osteoclast physiology	J:60625
	abnormal platelet activation	J:24346
	abnormal skeleton morphology	J:60625
	abnormal skeleton physiology	J:60625
	abnormal wound healing	J:24346
	decreased inflammatory response	J:24346
	impaired neutrophil chemotaxis	J:24346
	impaired neutrophil recruitment	J:24346
	increased bleeding time	J:24346
	increased compact bone thickness	J:60625
	increased leukocyte cell number	J:24346
	increased neutrophil cell number	J:24346
	osteopetrosis	J:60625
	premature death	J:52545
Gsn^tm1Djk/Gsn^tm1Djk involves: 129S4/SvJae * BALB/c	abnormal branching of the mammary ductal tree	J:64868
	abnormal mammary duct terminal end bud morphology	J:64868
	abnormal mammary gland growth during pregnancy	J:64868
	lethality throughout fetal growth and development, complete penetrance	J:64868
Gsn^tm1Djk/Gsn^tm1Djk involves: 129S4/SvJae * C57BL/6	abnormal nervous system electrophysiology	J:52545
	abnormal pulmonary circulation	J:94614
	increased cerebral infarct size	J:52545
	increased susceptibility to ischemic brain injury	J:52545
	increased vascular permeability	J:94614

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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