H2-I Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2-I
H2 I region, includes H2-Aa, Ab, Bl, Ea, Eb, Eb2, Ob, Pb
MGI:95903

7 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(H2-Ea)16Dim/? involves: C57BL/6 * SJL	increased immunoglobulin level	J:111128
Tg(H2-Ea^d)5Lt/0 NOD/ShiLt-Tg(H2-Ea^d)5Lt	autoimmune response	J:36435
	decreased interferon-gamma secretion	J:36435
	decreased susceptibility to autoimmune diabetes	J:36435
	increased interleukin-4 secretion	J:36435
	periinsulitis	J:36435
Tg(H2-Ea^d)12Lt/0 NOD/ShiLt-Tg(H2-Ea^d)12Lt	autoimmune response	J:36435
	decreased interferon-gamma secretion	J:36435
	decreased susceptibility to autoimmune diabetes	J:36435
	increased interleukin-4 secretion	J:36435
	insulitis	J:36435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24