H2-M3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2-M3
histocompatibility 2, M region locus 3
MGI:95915

8 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
H2-M3^tm1Crw/H2-M3^tm1Crw B6.129-H2-M3^tm1Crw	abnormal CD8-positive, alpha beta T cell morphology	J:118960
	abnormal cytotoxic T cell physiology	J:118960
	abnormal innate immunity	J:118960
	decreased activated T cell number	J:118960
	decreased interferon-gamma secretion	J:118960
	decreased macrophage nitric oxide production	J:118960
	impaired natural killer cell mediated cytotoxicity	J:118960
	increased susceptibility to bacterial infection	J:118960

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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