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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
H2-DMa
histocompatibility 2, class II, locus DMa
MGI:95921
18 phenotypes from 5 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
H2-DMatm1Doi/H2-DMatm1Doi
involves: 129S2/SvPas * C57BL/6
abnormal professional antigen presenting cell physiology J:31624
normal immune system phenotype J:31624
H2-DMatm1Liz/H2-DMatm1Liz
involves: BALB/cJ
abnormal antigen presentation via MHC class II J:113714
abnormal CD4-positive, alpha beta T cell morphology J:113714
abnormal professional antigen presenting cell physiology J:111565, J:113714
defective assembly of class II molecules J:113714
H2-DMatm1Lkrl/H2-DMatm1Lkrl
involves: 129P2/OlaHsd
abnormal antigen presentation J:31786
abnormal CD4-positive, alpha-beta T cell physiology J:31786
abnormal positive T cell selection J:31786
abnormal professional antigen presenting cell physiology J:31786
decreased CD4-positive, alpha-beta T cell number J:31786
H2-DMatm1Luc/H2-DMatm1Luc
B6.129S4-H2-Dmatm1Luc
abnormal antigen presentation J:125654
abnormal T-helper 1 physiology J:125654
decreased susceptibility to experimental autoimmune encephalomyelitis J:125654
decreased susceptibility to type IV hypersensitivity reaction J:125654
H2-DMatm1Luc/H2-DMatm1Luc
involves: 129S4/SvJae
abnormal antigen presentation via MHC class II J:31625
abnormal CD4-positive, alpha-beta T cell physiology J:31625
abnormal level of surface class II molecules J:45185
abnormal positive T cell selection J:125548
decreased body size J:31625
decreased CD4-positive, alpha-beta T cell number J:31625, J:45185
decreased interferon-gamma secretion J:45185
increased susceptibility to bacterial infection J:45185
premature death J:31625
H2-DMatm1Luc/H2-DMatm1Luc
involves: 129S4/SvJae * C57BL/6
abnormal antigen presentation J:72243
decreased susceptibility to experimental autoimmune encephalomyelitis J:72243
H2-DMatm2Liz/H2-DMatm2Liz
involves: C57BL/6 * C57BL/10 * C57BR * CBA
abnormal antigen presentation via MHC class II J:111565
abnormal professional antigen presenting cell physiology J:111565
decreased T cell proliferation J:111565

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory