H2-Oa Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2-Oa
histocompatibility 2, O region alpha locus
MGI:95924

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
H2-Oa/Brd2^{Tg(otx2-lacZ)F5pImat}/H2-Oa/Brd2^{Tg(otx2-lacZ)F5pImat} involves: CD-1	abnormal cell cycle	J:188139
	abnormal craniofacial morphology	J:188139
	abnormal embryonic neuroepithelial layer differentiation	J:188139
	abnormal embryonic neuroepithelium morphology	J:188139
	abnormal neural tube morphology	J:188139
	embryonic growth retardation	J:188139
	embryonic lethality during organogenesis, complete penetrance	J:188139
	increased embryonic neuroepithelium apoptosis	J:188139
	increased embryonic neuroepithelium thickness	J:188139
H2-Oa^tm1Dma/H2-Oa^tm1Dma involves: 129/Sv * C57BL/6	abnormal antigen presentation via MHC class II	J:65235
H2-Oa^tm1Dma/H2-Oa^tm1Dma involves: 129/Sv * C57BL/6	increased CD4-positive, alpha-beta T cell number	J:65235
H2-Oa^tm1Lkar/H2-Oa^tm1Lkar involves: 129P2/OlaHsd	abnormal antigen presentation via MHC class II	J:85084
	normal immune system phenotype	J:85084
	increased IgG1 level	J:85084

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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