About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hba
hemoglobin alpha chain complex
MGI:96014
78 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Hba-a1tm1Ywk/Hbath-J
involves: 129X1/SvJ * C57BL/6J 		abnormal erythrocyte morphology J:35018
abnormal hemoglobin J:35018
anisocytosis J:35018
decreased fetal size J:35018
hemolytic anemia J:35018
leptocytosis J:35018
pallor J:35018
perinatal lethality, complete penetrance J:35018
poikilocytosis J:35018
polychromatophilia J:35018
reticulocytosis J:35018
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow
Not Specified 		abnormal erythrocyte morphology J:134980
abnormal kidney corticomedullary boundary morphology J:134980
abnormal Kupffer cell morphology J:134980
abnormal liver morphology J:134980
abnormal spleen white pulp morphology J:134980
anemia J:137709
anisocytosis J:134980
decreased erythrocyte cell number J:134980
decreased hematocrit J:134980
decreased hemoglobin content J:134980
decreased urine osmolality J:134980
enlarged spleen J:134980
extramedullary hematopoiesis J:134980
focal hepatic necrosis J:134980
increased liver iron level J:134980
increased spleen red pulp amount J:134980
kidney vascular congestion J:134980
liver vascular congestion J:134980
poikilocytosis J:134980
polychromatophilia J:134980
reticulocytosis J:134980
spleen vascular congestion J:134980
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow
Slc12a4Rbc10/Slc12a4+
involves: 129 * BALB/c * C57BL/6J 		abnormal erythrocyte physiology J:227339
abnormal liver morphology J:227339
abnormal lung morphology J:227339
abnormal pulmonary circulation J:227339
abnormal renal tubule morphology J:227339
enlarged spleen J:227339
hepatic necrosis J:227339
increased mesangial cell number J:227339
liver inflammation J:227339
microcytic anemia J:227339
premature death J:227339
reticulocytosis J:227339
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm2(HBG1,HBB*)Tow
Slc12a4Rbc10/Slc12a4Rbc10
involves: 129 * BALB/c * C57BL/6J 		premature death J:227339
preweaning lethality, incomplete penetrance J:227339
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm3(HBG1,HBB)Tow
Not Specified 		anemia J:137709
normal hematopoietic system phenotype J:134980
normal liver/biliary system phenotype J:134980
normal renal/urinary system phenotype J:134980
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBB*)Tow/Hbbtm3(HBG1,HBB)Tow
Slc12a4Rbc10/Slc12a4Rbc10
involves: 129 * BALB/c * C57BL/6J 		microcytic anemia J:227339
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm2(HBG1,HBD,HBB*)Ryan
Not Specified 		abnormal proerythroblast morphology J:148521
anemia J:148521
anisopoikilocytosis J:148521
decreased hemoglobin content J:148521
decreased mean corpuscular volume J:148521
extramedullary hematopoiesis J:148521
hemolytic anemia J:148521
increased circulating bilirubin level J:148521
intermingled spleen red and white pulp J:148521
low mean erythrocyte cell number J:148521
polychromatophilia J:148521
premature death J:148521
reticulocytosis J:148521
spherocytosis J:148521
spleen hyperplasia J:148521
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm2(HBG1,HBD,HBB*)Ryan/Hbbtm3(HBG1,HBB)Tow
Not Specified 		abnormal definitive hematopoiesis J:148521
decreased hemoglobin content J:148521
decreased mean corpuscular volume J:148521
high mean erythrocyte cell number J:148521
reticulocytosis J:148521
spleen hyperplasia J:148521
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm3(HBG1,HBB)Tow/Hbbtm3(HBG1,HBB)Tow
Not Specified 		anemia J:137709
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm4(HBB*)Tow/Hbbtm4(HBB*)Tow
Not Specified 		abnormal erythrocyte physiology J:137709
anemia J:137709
normal cardiovascular system phenotype J:137709
Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm5(HBG1,HBB*)Tow/Hbbtm5(HBG1,HBB*)Tow
Not Specified 		abnormal erythrocyte physiology J:137709
anemia J:137709
normal cardiovascular system phenotype J:137709
Hbatm1Paz/Hba+
Hbbtm1Tow/Hbbtm1Tow
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal erythroid progenitor cell morphology J:204029
decreased erythroid progenitor cell number J:204029
Hbatm1Paz/Hbatm1Paz
Hbbtm1Tow/Hbb+
involves: 129S2/SvPas * 129S7/SvEvBrd 		normal hematopoietic system phenotype J:204029
Hbatm1Paz/Hbatm1Paz
Hbbtm1Tow/Hbbtm1Tow
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal embryonic erythrocyte morphology J:204029
abnormal embryonic erythropoiesis J:204029
abnormal erythroid progenitor cell morphology J:204029
decreased embryo size J:204029
decreased erythroid progenitor cell number J:204029
embryonic lethality during organogenesis, complete penetrance J:204029
liver hypoplasia J:204029
microcytic anemia J:204029
microcytosis J:204029
pallor J:204029
small liver J:204029
Hbatm1Paz/Hbatm1Paz
Hbbtm1Tow/Hbbtm1Tow
Tg(HBA-HBBs)41Paz/0
involves: 129 * Black Swiss * C57BL/6 * DBA/2 * FVB/N 		abnormal penile erection J:135978
priapism J:135978
Hbatm1Paz/Hbatm1Paz
Hbbtm1Tow/Hbbtm1Tow
Tg(HBA-HBBs)41Paz/?
involves: 129S2/SvPas * 129S7/SvEvBrd * Black Swiss * C57BL/6 * DBA/2* FVB/N 		abnormal erythrocyte morphology J:44161
abnormal hemoglobin J:44161
abnormal kidney vasculature morphology J:44161
abnormal liver vasculature morphology J:44161
abnormal lung vasculature morphology J:44161
anemia J:44161
anisopoikilocytosis J:44161
decreased erythrocyte osmotic fragility J:44161
decreased hematocrit J:44161
decreased mean corpuscular hemoglobin J:44161
decreased mean corpuscular hemoglobin concentration J:44161
decreased mean corpuscular volume J:44161
hypoxia J:44161
increased heart weight J:44161
increased kidney iron level J:44161
increased kidney weight J:44161
increased liver iron level J:44161
increased spleen weight J:44161
kidney atrophy J:44161
kidney cyst J:44161
neonatal lethality, incomplete penetrance J:44161
renal fibrosis J:44161
reticulocytosis J:44161
spleen vascular congestion J:44161
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory