Hbb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hbb
hemoglobin beta chain complex
MGI:96020

36 phenotypes from 8 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hbb^d3th/Hbb^d3th involves: C57BL/6 * DBA/2J	abnormal erythrocyte morphology	J:7209
	abnormal hemoglobin	J:7209
	abnormal hemoglobin content	J:7209
	anisocytosis	J:7209
	anisopoikilocytosis	J:7209
	decreased hematocrit	J:7209
	decreased litter size	J:7209
	decreased mean corpuscular hemoglobin	J:7209
	decreased mean corpuscular volume	J:7209
	hyperchromasia	J:7209
	low mean erythrocyte cell number	J:7209
	microcytosis	J:7209
	poikilocytosis	J:7209
	postnatal lethality, incomplete penetrance	J:7209
	reticulocytosis	J:7209
Hbb^d3th/Hbb^d3th Not Specified	decreased hematocrit	J:136653
	decreased mean corpuscular volume	J:136653
	reticulocytosis	J:136653
Hbb^d4/Hbb⁺ involves: 101/H	increased blood oxygen capacity	J:7972
	increased erythrocyte cell number	J:7972
	increased hematocrit	J:7972
	increased mean corpuscular hemoglobin concentration	J:7972
	polycythemia	J:7972
Hbb^d4/Hbb^d4 involves: 101/H	abnormal bone marrow cell physiology	J:7972
	abnormal hemoglobin	J:7972
	abnormal macrophage morphology	J:7972
	abnormal skin appearance	J:7972
	cardiac hypertrophy	J:7972
	decreased litter size	J:7972
	enlarged spleen	J:7972
	female infertility	J:7972
	increased blood oxygen capacity	J:7972
	increased erythrocyte cell number	J:7972
	increased hematocrit	J:7972
	increased mean corpuscular hemoglobin concentration	J:7972
	increased spleen red pulp amount	J:7972
	polycythemia	J:7972
	postnatal lethality, incomplete penetrance	J:7972
	reddish skin	J:7972
Hbb^d5/Hbb^d5 involves: 101/H	no abnormal phenotype detected	J:180204
Hbb^d6/Hbb^d6 involves: 101/H	no abnormal phenotype detected	J:180204
Hbb^d7/Hbb^d7 involves: C3H/HeH	no abnormal phenotype detected	J:180204
Hbb^s/Hbb^s involves: C57BL/6	no abnormal phenotype detected	J:118857
Hbb^tm1Tow/Hbb⁺ involves: 129S2/SvPas * C57BL/6	anemia	J:29087
	anisopoikilocytosis	J:29087
	decreased hemoglobin content	J:29087
	enlarged spleen	J:29087
	increased bone marrow cell number	J:29087
	increased spleen weight	J:29087
	reticulocytosis	J:29087
Hbb^tm1Tow/Hbb^tm1Tow involves: 129S2/SvPas * C57BL/6	prenatal lethality, complete penetrance	J:29087
Hbb^tm1Unc/Hbb^tm1Unc involves: 129P2/OlaHsd * C57BL/6J	abnormal erythrocyte morphology	J:4932
	anemia	J:4932
	decreased hematocrit	J:4932
	decreased mean corpuscular hemoglobin	J:4932
	pallor	J:4932
	perinatal lethality, complete penetrance	J:4932
	poikilocytosis	J:4932
	reticulocytosis	J:4932

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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