About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hbb-b1
hemoglobin, beta adult major chain
MGI:96021
54 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ahsptm1.1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		anemia J:94421
decreased hematocrit J:94421
pallor J:94421
Ahsptm1.1Mjwe/Ahsptm1.1Mjwe
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal erythrocyte morphology J:94421
anemia J:94421
anisocytosis J:94421
decreased hematocrit J:94421
decreased mean corpuscular volume J:94421
increased hemoglobin concentration distribution width J:94421
increased nucleated erythrocyte cell number J:94421
increased number of Heinz bodies J:94421
pallor J:94421
prenatal lethality, incomplete penetrance J:94421
Ahsptm1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		anemia J:94421
decreased hematocrit J:94421
pallor J:94421
Ahsptm1Mjwe/Ahsptm1Mjwe
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal erythrocyte morphology J:94421
anemia J:94421
anisocytosis J:94421
decreased hematocrit J:94421
decreased mean corpuscular volume J:94421
increased hemoglobin concentration distribution width J:94421
increased nucleated erythrocyte cell number J:94421
increased number of Heinz bodies J:94421
pallor J:94421
prenatal lethality, incomplete penetrance J:94421
Erfetm1Lex/Erfetm1Lex
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6 		abnormal hormone level J:211331
decreased circulating iron level J:211331
decreased liver iron level J:211331
decreased mean corpuscular hemoglobin J:211331
decreased mean corpuscular volume J:211331
Hbb-b1MommeD7/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * FVB/N 		anemia J:190446
lethality throughout fetal growth and development, complete penetrance J:190446
Hbb-b1Rbc13/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		anemia J:190446
lethality throughout fetal growth and development, complete penetrance J:190446
Hbb-b1tm1Ley/Hbb-b1tm1Ley
129X1/SvJ-Hbb-b1tm1Ley 		normal hematopoietic system phenotype J:70187
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
B6;129-Hbb-b1tm1Unc Hbb-b2tm1Unc/J 		abnormal bone marrow morphology J:211331
abnormal spleen morphology J:211331
anemia J:211331
increased circulating erythropoietin level J:211331
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd 		abnormal erythropoiesis J:97548
abnormal reticulocyte cell number J:154187
anemia J:154187
decreased erythrocyte cell number J:97548
decreased hematocrit J:97548
decreased hemoglobin content J:97548
decreased mean corpuscular volume J:97548
enlarged spleen J:97548
increased circulating bilirubin level J:97548
increased erythroblast number J:154187
increased red blood cell distribution width J:97548
reticulocytosis J:97548
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		decreased hematocrit J:94421
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * C57BL/6J 		abnormal femur morphology J:30155
abnormal spleen morphology J:30155, J:88672
anemia J:30155, J:88672
decreased body weight J:30155
decreased compact bone thickness J:30155
decreased hematocrit J:30155
decreased hemoglobin content J:30155
decreased spleen white pulp amount J:30155
hemosiderosis J:30155, J:88672
increased bone marrow cell number J:30155
increased circulating bilirubin level J:30155
increased nucleated erythrocyte cell number J:30155
increased spleen weight J:30155
intermingled spleen red and white pulp J:30155
pallor J:30155
reticulocytosis J:30155
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * C57BL/6N 		abnormal erythrocyte morphology J:185154
abnormal erythropoiesis J:185154
decreased erythrocyte cell number J:185154
decreased hemoglobin content J:185154
decreased mean corpuscular volume J:185154
enlarged spleen J:185154
increased circulating erythropoietin level J:185154
increased erythroid progenitor cell number J:185154
increased liver iron level J:185154
increased spleen iron level J:185154
reticulocytosis J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tmprss6tm1Otin/Tmprss6+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N 		abnormal circulating erythropoietin level J:185154
abnormal erythrocyte cell number J:185154
abnormal erythrocyte morphology J:185154
abnormal hemoglobin content J:185154
abnormal liver iron level J:185154
abnormal spleen iron level J:185154
abnormal spleen size J:185154
decreased mean corpuscular volume J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tmprss6tm1Otin/Tmprss6tm1Otin
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N 		abnormal erythrocyte cell number J:185154
abnormal erythrocyte morphology J:185154
abnormal erythroid progenitor cell morphology J:185154
abnormal erythropoiesis J:185154
abnormal hemoglobin content J:185154
abnormal spleen size J:185154
normal homeostasis/metabolism phenotype J:185154
increased circulating erythropoietin level J:185154
reticulocytopenia J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tg(HBB*)L2Pai/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal erythropoiesis J:97548
anisocytosis J:97548
decreased erythrocyte cell number J:97548
decreased hematocrit J:97548
decreased hemoglobin content J:97548
decreased mean corpuscular volume J:97548
enlarged spleen J:97548
increased circulating bilirubin level J:97548
increased red blood cell distribution width J:97548
poikilocytosis J:97548
reticulocytosis J:97548
Hbb-b1tm1Unc/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J 		perinatal lethality, complete penetrance J:30155
Hbb-b1tm1Unc/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2tm1Unc
Tg(HBB*)L2Pai/0
involves: 129P2/OlaHsd * C57BL/6 		anemia J:97548
decreased fetal size J:97548
perinatal lethality, complete penetrance J:97548
Pax6Sey/Pax6Sey-Neu
Tg(Hbb-b1)83Clo/0
involves: 102 * C3H * C57BL * CBA/Ca * CD-1 * SJL 		abnormal craniofacial bone morphology J:43913
abnormal nasal capsule morphology J:43913
supernumerary incisors J:43913
Pax6Sey/Pax6Sey
Tg(Hbb-b1)83Clo/0
involves: C57BL * CBA/Ca * CD-1 * SJL 		abnormal craniofacial bone morphology J:43913
abnormal nasal capsule morphology J:43913
supernumerary incisors J:43913
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory