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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hbb-b2
hemoglobin, beta adult minor chain
MGI:96022
50 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ahsptm1.1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		anemia J:94421
decreased hematocrit J:94421
pallor J:94421
Ahsptm1.1Mjwe/Ahsptm1.1Mjwe
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal erythrocyte morphology J:94421
anemia J:94421
anisocytosis J:94421
decreased hematocrit J:94421
decreased mean corpuscular volume J:94421
increased hemoglobin concentration distribution width J:94421
increased nucleated erythrocyte cell number J:94421
increased number of Heinz bodies J:94421
pallor J:94421
prenatal lethality, incomplete penetrance J:94421
Ahsptm1Mjwe/Ahsp+
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		anemia J:94421
decreased hematocrit J:94421
pallor J:94421
Ahsptm1Mjwe/Ahsptm1Mjwe
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal erythrocyte morphology J:94421
anemia J:94421
anisocytosis J:94421
decreased hematocrit J:94421
decreased mean corpuscular volume J:94421
increased hemoglobin concentration distribution width J:94421
increased nucleated erythrocyte cell number J:94421
increased number of Heinz bodies J:94421
pallor J:94421
prenatal lethality, incomplete penetrance J:94421
Erfetm1Lex/Erfetm1Lex
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6 		abnormal hormone level J:211331
decreased circulating iron level J:211331
decreased liver iron level J:211331
decreased mean corpuscular hemoglobin J:211331
decreased mean corpuscular volume J:211331
Hbb-b1MommeD7/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * FVB/N 		anemia J:190446
lethality throughout fetal growth and development, complete penetrance J:190446
Hbb-b1Rbc13/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		anemia J:190446
lethality throughout fetal growth and development, complete penetrance J:190446
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
B6;129-Hbb-b1tm1Unc Hbb-b2tm1Unc/J 		abnormal bone marrow morphology J:211331
abnormal spleen morphology J:211331
anemia J:211331
increased circulating erythropoietin level J:211331
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd 		abnormal erythropoiesis J:97548
abnormal reticulocyte cell number J:154187
anemia J:154187
decreased erythrocyte cell number J:97548
decreased hematocrit J:97548
decreased hemoglobin content J:97548
decreased mean corpuscular volume J:97548
enlarged spleen J:97548
increased circulating bilirubin level J:97548
increased erythroblast number J:154187
increased red blood cell distribution width J:97548
reticulocytosis J:97548
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		decreased hematocrit J:94421
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * C57BL/6J 		abnormal femur morphology J:30155
abnormal spleen morphology J:30155, J:88672
anemia J:30155, J:88672
decreased body weight J:30155
decreased compact bone thickness J:30155
decreased hematocrit J:30155
decreased hemoglobin content J:30155
decreased spleen white pulp amount J:30155
hemosiderosis J:30155, J:88672
increased bone marrow cell number J:30155
increased circulating bilirubin level J:30155
increased nucleated erythrocyte cell number J:30155
increased spleen weight J:30155
intermingled spleen red and white pulp J:30155
pallor J:30155
reticulocytosis J:30155
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
involves: 129P2/OlaHsd * C57BL/6N 		abnormal erythrocyte morphology J:185154
abnormal erythropoiesis J:185154
decreased erythrocyte cell number J:185154
decreased hemoglobin content J:185154
decreased mean corpuscular volume J:185154
enlarged spleen J:185154
increased circulating erythropoietin level J:185154
increased erythroid progenitor cell number J:185154
increased liver iron level J:185154
increased spleen iron level J:185154
reticulocytosis J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tmprss6tm1Otin/Tmprss6+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N 		abnormal circulating erythropoietin level J:185154
abnormal erythrocyte cell number J:185154
abnormal erythrocyte morphology J:185154
abnormal hemoglobin content J:185154
abnormal liver iron level J:185154
abnormal spleen iron level J:185154
abnormal spleen size J:185154
decreased mean corpuscular volume J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tmprss6tm1Otin/Tmprss6tm1Otin
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N 		abnormal erythrocyte cell number J:185154
abnormal erythrocyte morphology J:185154
abnormal erythroid progenitor cell morphology J:185154
abnormal erythropoiesis J:185154
abnormal hemoglobin content J:185154
abnormal spleen size J:185154
normal homeostasis/metabolism phenotype J:185154
increased circulating erythropoietin level J:185154
reticulocytopenia J:185154
Hbb-b1tm1Unc/Hbb-b1+
Hbb-b2tm1Unc/Hbb-b2+
Tg(HBB*)L2Pai/0
involves: 129P2/OlaHsd * C57BL/6 		abnormal erythropoiesis J:97548
anisocytosis J:97548
decreased erythrocyte cell number J:97548
decreased hematocrit J:97548
decreased hemoglobin content J:97548
decreased mean corpuscular volume J:97548
enlarged spleen J:97548
increased circulating bilirubin level J:97548
increased red blood cell distribution width J:97548
poikilocytosis J:97548
reticulocytosis J:97548
Hbb-b1tm1Unc/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2tm1Unc
involves: 129P2/OlaHsd * C57BL/6J 		perinatal lethality, complete penetrance J:30155
Hbb-b1tm1Unc/Hbb-b1tm1Unc
Hbb-b2tm1Unc/Hbb-b2tm1Unc
Tg(HBB*)L2Pai/0
involves: 129P2/OlaHsd * C57BL/6 		anemia J:97548
decreased fetal size J:97548
perinatal lethality, complete penetrance J:97548
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory