About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hexb
hexosaminidase B
MGI:96074
53 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
B4galnt1tm1Rlp/B4galnt1+
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		impaired coordination J:53080
impaired righting response J:53080
B4galnt1tm1Rlp/B4galnt1tm1Rlp
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		abnormal macrophage morphology J:53080
abnormal neuron morphology J:53080
abnormal Purkinje cell morphology J:53080
abnormal renal tubule epithelium morphology J:53080
ataxia J:53080
impaired coordination J:53080
normal mortality/aging J:53080
Purkinje cell degeneration J:53080
seminiferous tubule degeneration J:53080
Ccl3tm1Unc/Ccl3+
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal motor coordination/balance J:90687
abnormal righting response J:90687
premature death J:90687
Ccl3tm1Unc/Ccl3tm1Unc
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal motor coordination/balance J:90687
abnormal righting response J:90687
abnormal tumor necrosis factor level J:90687
normal cellular phenotype J:90687
CNS inflammation J:90687
normal growth/size/body region phenotype J:90687
premature death J:90687
Fcer1gtm1Rav/Fcer1gtm1Rav
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal lipid level J:87617
normal behavior/neurological phenotype J:87617
decreased apoptosis J:87617
impaired coordination J:87617
increased immunoglobulin level J:87617
normal nervous system phenotype J:87617
premature death J:87617
Hexatm1Rlp/Hexatm1Rlp
Hexbtm1Rlp/Hexbtm1Rlp
involves: 129S4/SvJae * C57BL/6 		abnormal axial skeleton morphology J:36305
abnormal CNS glial cell morphology J:41920
abnormal cranium morphology J:36305, J:41920
abnormal digit morphology J:36305
abnormal eye morphology J:41920
abnormal mandible morphology J:36305
abnormal motor capabilities/coordination/movement J:36305
abnormal myelination J:41920
abnormal nervous system morphology J:36305
abnormal nervous system physiology J:41920
abnormal neuron morphology J:36305
abnormal rib morphology J:41920
abnormal thoracic cage shape J:36305
abnormal trabecular bone morphology J:41920
abnormal urine homeostasis J:36305
abnormal vertebrae morphology J:41920
broad snout J:36305
camptodactyly J:36305
cornea opacity J:36305
deafness J:36305
decreased length of long bones J:36305
decreased locomotor activity J:36305
decreased vertical activity J:36305
frontal bossing J:36305
impaired coordination J:36305
increased diameter of long bones J:36305
increased urine glycosaminoglycan level J:36305
infertility J:36305
kyphosis J:36305
postnatal growth retardation J:36305
premature death J:36305
shortened head J:36305
sporadic seizures J:36305
wide ribs J:36305
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory