About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Hmgcl
3-hydroxy-3-methylglutaryl-Coenzyme A lyase
MGI:96158
14 phenotypes from 2 alleles in 2 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Hmgcltm1Gam/Hmgcl+
either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)
abnormal hepatocyte morphology J:52117
Hmgcltm1Gam/Hmgcltm1Gam
either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6J) or (involves: 129P2/OlaHsd * CD-1)
abnormal heart morphology J:52117
abnormal hepatocyte mitochondrial morphology J:52117
abnormal hepatocyte morphology J:52117
abnormal placenta morphology J:52117
decreased embryo size J:52117
embryonic lethality during organogenesis, incomplete penetrance J:52117
Hmgcltm2Gam/Hmgcltm2Gam
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
B6.Cg-Hmgcltm2Gam Speer6-ps1Tg(Alb-cre)21Mgn
abnormal gluconeogenesis J:204294
abnormal hepatocyte mitochondrial morphology J:204294
abnormal hepatocyte physiology J:204294
normal homeostasis/metabolism phenotype J:204294
hypoglycemia J:204294
increased circulating ammonia level J:204294
increased circulating carnitine level J:204294
lethargy J:204294
premature death J:204294

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory