About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hmga1
high mobility group AT-hook 1
MGI:96160
43 phenotypes from 5 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Hmga1tm1Afus/Hmga1+
involves: 129S7/SvEvBrd * C57BL/6 		cardiac hypertrophy J:106702
enlarged spleen J:106702
Hmga1tm1Afus/Hmga1tm1Afus
involves: 129S7/SvEvBrd * C57BL/6 		abnormal myocardium layer morphology J:106702
cardiac hypertrophy J:106702
decreased body weight J:106702
enlarged spleen J:106702
heart left ventricle hypertrophy J:106702
increased B cell derived lymphoma incidence J:106702
increased leukemia incidence J:106702
lymphoid hyperplasia J:106702
myeloid hyperplasia J:106702
Hmga1tm1Brun/Hmga1+
Not Specified 		decreased circulating insulin level J:99652
decreased insulin secretion J:99652
impaired glucose tolerance J:99652
increased insulin sensitivity J:99652
insulin resistance J:99652
Hmga1tm1Brun/Hmga1tm1Brun
Not Specified 		abnormal pancreatic islet morphology J:99652
decreased circulating insulin level J:99652
decreased insulin secretion J:99652
impaired glucose tolerance J:99652
increased insulin sensitivity J:99652
insulin resistance J:99652
small pancreatic islets J:99652
Hmga1tm1Cha/Hmga1+
chimera involves: 129S1/Sv * C57BL/6J 		abnormal seminiferous tubule epithelium morphology J:84851
abnormal seminiferous tubule morphology J:84851
abnormal Sertoli cell morphology J:84851
abnormal spermatogenesis J:84851
azoospermia J:84851
decreased male germ cell number J:84851
male infertility J:84851
small epididymis J:84851
small seminiferous tubules J:84851
small testis J:84851
Hmga1tm2b(EUCOMM)Hmgu/Hmga1+
C57BL/6N-Hmga1tm2b(EUCOMM)Hmgu/Bay 		unresponsive to tactile stimuli J:211773
Hmga1tm2b(EUCOMM)Hmgu/Hmga1tm2b(EUCOMM)Hmgu
C57BL/6N-Hmga1tm2b(EUCOMM)Hmgu/Bay 		preweaning lethality, incomplete penetrance J:211773
unresponsive to tactile stimuli J:211773
Tg(H2-K-Hmga1)#Lmsr/0
involves: C57BL/6 * SJL 		abnormal endometrium morphology J:121308
abnormal intestine morphology J:184301
abnormal uterine cervix morphology J:90252
decreased locomotor activity J:90252
female infertility J:121308
increased intestinal mucosa thickness J:184301
increased leukemia incidence J:121308
increased leukocyte cell number J:90252
increased lymphoma incidence J:90252, J:121308
increased T cell acute lymphoblastic leukemia incidence J:90252
increased uterus leiomyoma incidence J:121308
increased uterus tumor incidence J:121308
intestine polyps J:184301
premature death J:90252
rectal prolapse J:90252
visceromegaly J:90252
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory