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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hoxa11
homeobox A11
MGI:96172
70 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hoxa11tm1Dmwe/Hoxa11+
Hoxc11tm1Mrc/Hoxc11+
Hoxd11tm1Mrc/Hoxd11+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 		female infertility J:140709
male infertility J:140709
Hoxa11tm1Mrc/Hoxa11+
Hoxd11tm1Mrc/Hoxd11+
involves: 129S7/SvEvBrd 		increased lumbar vertebrae number J:78766
Hoxa11tm1Mrc/Hoxa11+
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S7/SvEvBrd 		increased lumbar vertebrae number J:78766
Hoxa11tm1Mrc/Hoxa11+
Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc
involves: BALB/cJ 		normal skeleton phenotype J:78766
Hoxa11tm1Mrc/Hoxa11+
Hoxc11tm1Mrc/Hoxc11+
Hoxd11tm1Mrc/Hoxd11+
involves: 129S7/SvEvBrd 		abnormal reproductive system morphology J:88686
female infertility J:88686
male infertility J:88686
Hoxa11tm1Mrc/Hoxa11+
Hoxc11tm1Mrc/Hoxc11+
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S7/SvEvBrd 		abnormal reproductive system morphology J:88686
female infertility J:88686
male infertility J:88686
Hoxa11tm1Mrc/Hoxa11+
Hoxc11tm1Mrc/Hoxc11tm1Mrc
Hoxd11tm1Mrc/Hoxd11+
involves: 129S7/SvEvBrd 		abnormal reproductive system morphology J:88686
female infertility J:88686
male infertility J:88686
Hoxa11tm1Mrc/Hoxa11+
Hoxc11tm1Mrc/Hoxc11tm1Mrc
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S7/SvEvBrd 		abnormal ureteric bud invasion J:88686
ectopic kidney J:88686
renal hypoplasia J:88686
single kidney J:88686
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxc11tm1Mrc/Hoxc11+
Hoxd11tm1Mrc/Hoxd11+
involves: 129S7/SvEvBrd 		abnormal reproductive system morphology J:88686
female infertility J:88686
male infertility J:88686
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxc11tm1Mrc/Hoxc11+
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S7/SvEvBrd 		abnormal ureteric bud invasion J:88686
ectopic kidney J:88686
renal hypoplasia J:88686
single kidney J:88686
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxc11tm1Mrc/Hoxc11tm1Mrc
involves: 129S7/SvEvBrd 		renal hypoplasia J:88686
single kidney J:88686
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxc11tm1Mrc/Hoxc11tm1Mrc
Hoxd11tm1Mrc/Hoxd11+
involves: 129S7/SvEvBrd 		abnormal ureteric bud invasion J:88686
ectopic kidney J:88686
renal hypoplasia J:88686
single kidney J:88686
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxc11tm1Mrc/Hoxc11tm1Mrc
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S7/SvEvBrd 		abnormal kidney development J:88686
absent metanephros J:88686
absent ureteric bud J:88686
increased metanephric mesenchyme apoptosis J:88686
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxd11tm1Mrc/Hoxd11+
involves: 129S7/SvEvBrd 		fused carpal bones J:78766
increased diameter of radius J:78766
increased diameter of ulna J:78766
increased lumbar vertebrae number J:78766
short radius J:78766
short ulna J:78766
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S7/SvEvBrd 		abnormal ureter development J:88686
increased diameter of radius J:78766
increased diameter of ulna J:78766
increased lumbar vertebrae number J:78766
renal hypoplasia J:88686
short radius J:78766
short ulna J:78766
single kidney J:88686
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc
involves: 129S7/SvEvBrd * BALB/cJ 		fused carpal bones J:78766
increased diameter of radius J:78766
increased diameter of ulna J:78766
increased lumbar vertebrae number J:78766
short radius J:78766
short ulna J:78766
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
involves: BALB/cJ 		female infertility J:78766
increased diameter of radius J:78766
increased diameter of ulna J:78766
reduced male fertility J:78766
short radius J:78766
short ulna J:78766
normal skeleton phenotype J:78766
Hoxa11tm1Mrc/Hoxa11tm1Mrc
Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc
involves: BALB/cJ 		female infertility J:78766
normal limbs/digits/tail phenotype J:78766
male infertility J:78766
normal skeleton phenotype J:78766
Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxd+
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL 		normal skeleton phenotype J:47900
Hoxa11tm1Ssp/Hoxa11+
Hoxdtm3Ddu/Hoxdtm3Ddu
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL 		abnormal fibula morphology J:47900
abnormal radius morphology J:47900
abnormal tibia morphology J:47900
abnormal ulna morphology J:47900
Hoxa11tm1Ssp/Hoxa11+
Hoxd11tm1Mrc/Hoxd11+
mixed 		fused carpal bones J:26492
sacral vertebral transformation J:26492
Hoxa11tm1Ssp/Hoxa11+
Hoxd11tm2.1Ddu/Hoxd11+
involves: 129S2/SvPas * C57BL/6J 		abnormal carpal bone morphology J:41828
abnormal lumbar vertebrae morphology J:41828
increased lumbar vertebrae number J:41828
Hoxa11tm1Ssp/Hoxa11+
Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
involves: 129S2/SvPas * C57BL/6J 		abnormal lumbar vertebrae morphology J:41828
increased lumbar vertebrae number J:41828
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxc11tm1Mrc/Hoxc11+
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal sacral vertebrae morphology J:84456
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxc11tm1Mrc/Hoxc11tm1Mrc
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal forelimb zeugopod morphology J:84456
abnormal hindlimb zeugopod morphology J:84456
abnormal pelvic girdle bone morphology J:84456
absent sacral vertebrae J:84456
sacral vertebral transformation J:84456, J:124112
normal skeleton phenotype J:84456
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxd11tm1Mrc/Hoxd11+
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal forelimb zeugopod morphology J:71402
short radius J:71402
short ulna J:71402
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxd11tm1Mrc/Hoxd11tm1Mrc
involves: 129S2/SvPas * 129S7/SvEvBrd 		abnormal calcaneum morphology J:71402
abnormal carpal bone morphology J:71402
abnormal forelimb zeugopod morphology J:71402
abnormal renal tubule morphology J:71402
decreased survivor rate J:71402
dilated renal tubule J:71402
kidney cyst J:71402
kidney medulla hypoplasia J:71402
neonatal lethality, incomplete penetrance J:71402
postnatal lethality, incomplete penetrance J:71402
premature death J:71402
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxd11tm1Mrc/Hoxd11tm1Mrc
mixed 		abnormal autopod rotation J:26492
abnormal carpal bone morphology J:26492
abnormal digit morphology J:26492
abnormal fibula morphology J:26492
abnormal forelimb zeugopod morphology J:26492
abnormal kidney cortex morphology J:26492
abnormal kidney development J:69851
abnormal kidney medulla development J:26492
abnormal kidney morphology J:69851
abnormal limb bone morphology J:26492
abnormal long bone morphology J:26492
abnormal metanephric mesenchyme morphology J:69851
abnormal phalanx morphology J:26492
abnormal sacral vertebrae morphology J:26492
abnormal tarsal bone morphology J:26492
abnormal ureter development J:69851
abnormal vas deferens morphology J:26492
abnormal vertebrae morphology J:26492
absent carpal bone J:26492
absent kidney J:26492
absent radius J:26492
absent ulna J:26492
decreased caudal vertebrae number J:26492
decreased renal tubule number J:26492
decreased sacral vertebrae number J:26492
impaired branching involved in ureteric bud morphogenesis J:69851
increased diameter of fibula J:69851
increased lumbar vertebrae number J:26492
kidney papillary hypoplasia J:26492
perinatal lethality, incomplete penetrance J:26492
renal hypoplasia J:26492
sacral vertebral transformation J:26492
short metacarpal bones J:26492
syndactyly J:26492
thoracic vertebral transformation J:26492
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxd11tm2.1Ddu/Hoxd11+
involves: 129S2/SvPas * C57BL/6J 		abnormal carpal bone morphology J:41828
abnormal lumbar vertebrae morphology J:41828
increased lumbar vertebrae number J:41828
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
involves: 129S2/SvPas * C57BL/6J 		abnormal carpal bone morphology J:41828
abnormal lumbar vertebrae morphology J:41828
abnormal radius morphology J:41828
abnormal ulna morphology J:41828
fused carpal bones J:41828
increased lumbar vertebrae number J:41828
Hoxa11tm1Ssp/Hoxa11tm1Ssp
Hoxdtm3Ddu/Hoxdtm3Ddu
involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL 		abnormal fibula morphology J:47900
abnormal tibia morphology J:47900
increased diameter of fibula J:47900
increased diameter of radius J:47900
increased diameter of tibia J:47900
increased diameter of ulna J:47900
Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp
Hoxd11tm1Mrc/Hoxd11+
either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ) 		abnormal calcaneum morphology J:71402
abnormal forelimb zeugopod morphology J:71402
female infertility J:71402
normal reproductive system phenotype J:71402
Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp
Hoxd11tm1Mrc/Hoxd11tm1Mrc
either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ) 		abnormal calcaneum morphology J:71402
abnormal carpal bone morphology J:71402
abnormal forelimb zeugopod morphology J:71402
abnormal kidney morphology J:71402
abnormal renal tubule morphology J:71402
decreased survivor rate J:71402
dilated renal tubule J:71402
female infertility J:71402
kidney cyst J:71402
kidney medulla hypoplasia J:71402
postnatal lethality, incomplete penetrance J:71402
premature death J:71402
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory