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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hoxb1
homeobox B1
MGI:96182
36 phenotypes from 12 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hoxb1tm1(cre)Og/Hoxb1tm1(cre)Og
involves: 129S/SvEv 		abnormal craniofacial morphology J:100238
abnormal nervous system morphology J:100238
normal behavior/neurological phenotype J:130927
Hoxb1tm1.1Mist/Hoxb1tm1.1Mist
B6.129S2-Hoxb1tm1.1Mist/Cnrm 		abnormal cochlear VIII nucleus morphology J:82809
abnormal facial motor nucleus morphology J:82809
Hoxb1tm1Brd/Hoxb1tm1Brd
involves: 129S7/SvEvBrd * C57BL/6 		abnormal axon guidance J:37450
abnormal facial nerve morphology J:37450
abnormal neuron differentiation J:37450
abnormal rhombomere 4 morphology J:37450
neonatal lethality, incomplete penetrance J:37450
Hoxb1tm1Mrc/Hoxb1tm1Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal buccinator muscle morphology J:36235
abnormal depressor anguli oris muscle morphology J:36235
abnormal digastric posterior belly morphology J:36235
abnormal facial nerve morphology J:36235
abnormal lower lip morphology J:36235
abnormal masseter muscle morphology J:36235
abnormal neuron differentiation J:36235
abnormal temporalis muscle morphology J:36235
abnormal tooth morphology J:36235
abnormal zygomaticus muscle morphology J:36235
absent facial muscle J:36235
absent facial nuclei J:36235
absent levator nasolabialis muscle J:36235
decreased body size J:36235
facial muscle degeneration J:36235
facial paralysis J:36235
narrow face J:36235
normal nervous system phenotype J:36235
postnatal lethality, incomplete penetrance J:36235
small facial motor nucleus J:36235
Hoxb1tm2Brd/Hoxb1tm2Brd
involves: 129S7/SvEvBrd * C57BL/6 		abnormal axon guidance J:37450
abnormal facial nerve morphology J:37450
abnormal neuron differentiation J:37450
abnormal rhombomere 4 morphology J:37450
neonatal lethality, incomplete penetrance J:37450
Hoxb1tm2Mrc/Hoxb1tm2Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal buccinator muscle morphology J:36235
abnormal depressor anguli oris muscle morphology J:36235
abnormal digastric posterior belly morphology J:36235
abnormal facial nerve morphology J:36235
abnormal lower lip morphology J:36235
abnormal masseter muscle morphology J:36235
abnormal neuron differentiation J:36235
abnormal temporalis muscle morphology J:36235
abnormal tooth morphology J:36235
abnormal zygomaticus muscle morphology J:36235
absent facial muscle J:36235
absent facial nuclei J:36235
absent levator nasolabialis muscle J:36235
decreased body size J:36235
facial muscle degeneration J:36235
facial paralysis J:36235
narrow face J:36235
neonatal lethality, incomplete penetrance J:36235
normal nervous system phenotype J:36235
postnatal lethality, incomplete penetrance J:36235
small facial motor nucleus J:36235
Hoxb1tm3Mrc/Hoxb1tm3Mrc
Not Specified 		abnormal craniofacial morphology J:41540
abnormal nervous system morphology J:41540
Hoxb1tm5Mrc/Hoxb1tm5Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		absent facial nerve J:119279
absent facial nuclei J:119279
Hoxb1tm5Mrc/Hoxb1tm5Mrc
Not Specified 		decreased sensory neuron number J:88581
Hoxb1tm5Mrc/Hoxb1tm7Mrc
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Not Specified 		abnormal blinking J:91364
abnormal facial nerve morphology J:91364
abnormal reflex J:91364
abnormal vibrissae reflex J:91364
decreased motor neuron number J:91364
paralysis J:91364
Hoxb1tm5Mrc/Hoxb1tm7Mrc
Tfap2atm1(cre)Moon/Tfap2a+
involves: 129S1/Sv * 129X1/SvJ 		normal behavior/neurological phenotype J:91364
decreased motor neuron number J:91364
Hoxb1tm5Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 		no abnormal phenotype detected J:119279
Hoxb1tm5Mrc/Hoxb1tm9Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal reflex J:119279
Hoxb1tm6(cre)Mrc/Hoxb1tm6(cre)Mrc
involves: 129 		no abnormal phenotype detected J:84448
Hoxb1tm7Mrc/Hoxb1tm7Mrc
Not Specified 		no abnormal phenotype detected J:91364
Hoxb1tm8(Hoxa1)Mrc/Hoxb1tm8(Hoxa1)Mrc
involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 		postnatal lethality, incomplete penetrance J:119279
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory