Hoxb4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hoxb4
homeobox B4
MGI:96185

35 phenotypes from 8 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hoxb4^tm1.1Karl/Hoxb4^tm1.1Karl involves: 129 * C57BL/6J	abnormal definitive hematopoiesis	J:90976
	decreased bone marrow cell number	J:90976
	decreased erythrocyte cell number	J:90976
	decreased hemoglobin content	J:90976
	spleen hypoplasia	J:90976
Hoxb4^tm1.1Mev/Hoxb4^tm1.1Mev involves: 129	no abnormal phenotype detected	J:170503
Hoxb4^tm1Bay/Hoxb4^tm1Bay 129S/SvEv-Hoxb4^tm1Bay	abnormal cervical axis morphology	J:4612
	abnormal sternebra morphology	J:4612
	cervical vertebral transformation	J:4612
	neonatal lethality, complete penetrance	J:4612
	split sternum	J:4612
Hoxb4^tm1Bay/Hoxb4^tm1Bay involves: 129S7/SvEvBrd * C57BL/6J	abnormal cervical axis morphology	J:4612
	abnormal chest morphology	J:4612
	abnormal sternebra morphology	J:4612
	cervical vertebral transformation	J:4612
	decreased body size	J:4612
	decreased survivor rate	J:4612
	diaphragmatic hernia	J:4612
	prenatal lethality, incomplete penetrance	J:4612
	split sternum	J:4612
Hoxb4^tm1Karl/Hoxb4^tm1Karl involves: 129 * C57BL/6J	no abnormal phenotype detected	J:90976
Hoxb4^tm1Nrm/Hoxb4⁺ involves: 129S7/SvEvBrd * C57BL/6	abnormal body wall morphology	J:71389
Hoxb4^tm1Nrm/Hoxb4^tm1Nrm involves: 129S7/SvEvBrd * C57BL/6	abnormal abdominal wall morphology	J:71389
	abnormal body wall morphology	J:71389
	abnormal cervical vertebrae morphology	J:71389
	abnormal heart morphology	J:71389
	abnormal heart position or orientation	J:71389
	abnormal sternum morphology	J:37682, J:71389
	abnormal ventral body wall morphology	J:37682, J:71389
	absent pericardium	J:71389
	decreased body size	J:71389
	diaphragmatic hernia	J:71389
	dilated heart ventricle	J:71389
	edema	J:71389
	neonatal lethality, incomplete penetrance	J:37682, J:71389
	pallor	J:71389
	respiratory distress	J:71389
	split sternum	J:71389
	thin interventricular septum	J:71389
	thin ventricular wall	J:71389
Hoxb4^tm2.1Nrm/Hoxb4^tm2.1Nrm involves: 129 * C57BL/6	abnormal cervical vertebrae morphology	J:71389
Hoxb4^tm2Bay/Hoxb4^tm2Bay involves: 129S7/SvEvBrd * C57BL/6J	abnormal cervical axis morphology	J:4612
	cervical vertebral transformation	J:4612
	normal growth/size/body region phenotype	J:4612
	normal mortality/aging	J:4612
	normal muscle phenotype	J:4612
	normal skeleton phenotype	J:4612
Hoxb4^tm2Nrm/Hoxb4^tm2Nrm involves: 129 * C57BL/6	abnormal cervical vertebrae morphology	J:71389
	abnormal ventral body wall morphology	J:71389
	split sternum	J:71389

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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