Hoxb8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hoxb8
homeobox B8
MGI:96189

30 phenotypes from 8 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hoxb8^tm1.1Jdes/Hoxb8⁺ involves: 129P2/OlaHsd * FVB	abnormal dorsal root ganglion morphology	J:58621
	abnormal spinal nerve morphology	J:58621
	abnormal sternocostal joint morphology	J:58621
Hoxb8^tm1.1Jdes/Hoxb8^tm1.1Jdes involves: 129P2/OlaHsd * FVB	abnormal dorsal root ganglion morphology	J:58621
	abnormal gait	J:58621
	abnormal rib morphology	J:68720
	abnormal sternocostal joint morphology	J:58621
	abnormal sternum morphology	J:68720
	asymmetric rib joints	J:68720
	cervical vertebral transformation	J:68720
	limb grasping	J:58621
	postnatal growth retardation	J:58621
	skin lesions	J:58621
Hoxb8^tm1.1Mrc/Hoxb8^tm1.1Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal coat appearance	J:73745
	abnormal skin condition	J:73745
	abnormal sleep pattern	J:73745
	increased grooming behavior	J:73745
	normal nervous system phenotype	J:73745
	normal skeleton phenotype	J:73745
Hoxb8^tm1.1Mrc/Hoxb8^tm1.1Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal grooming behavior	J:162102
	abnormal microglial cell morphology	J:162102
	abnormal spinal cord dorsal horn morphology	J:162102
	focal hair loss	J:162102
	increased grooming behavior	J:162102
	increased thermal nociceptive threshold	J:162102
	skin lesions	J:162102
Hoxb8^tm1Jdes/Hoxb8^tm1Jdes involves: 129P2/OlaHsd * FVB	abnormal dorsal root ganglion morphology	J:58621
	abnormal gait	J:58621
	abnormal rib morphology	J:58621
	abnormal vertebral column morphology	J:58621
	limb grasping	J:58621
	postnatal growth retardation	J:58621
	skin lesions	J:58621
Hoxb8^tm1Mrc/Hoxb8^tm1Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal coat appearance	J:73745
	abnormal rib development	J:73745
	abnormal skin condition	J:73745
	increased grooming behavior	J:73745
Hoxb8^tm1Omm/Hoxb8⁺ involves: 129S7/SvEvBrd	thoracic vertebral transformation	J:86684
Hoxb8^tm1Omm/Hoxb8⁺ involves: 129S7/SvEvBrd * C57BL/6	thoracic vertebral transformation	J:86684
Hoxb8^tm1Omm/Hoxb8^tm1Omm involves: 129S7/SvEvBrd	abnormal rib morphology	J:86684
	abnormal sternocostal joint morphology	J:86684
	decreased sternebra number	J:86684
	rib fusion	J:86684
	thoracic vertebral transformation	J:86684
Hoxb8^tm1Omm/Hoxb8^tm1Omm involves: 129S7/SvEvBrd * C57BL/6	abnormal rib morphology	J:86684
	abnormal sternocostal joint morphology	J:86684
	abnormal tooth morphology	J:86684
	decreased sternebra number	J:86684
	premature death	J:86684
	rib fusion	J:86684
	thoracic vertebral transformation	J:86684
Hoxb8^tm2Jdes/Hoxb8^tm2Jdes involves: 129P2/OlaHsd * FVB	limb grasping	J:58621
Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc}/Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc} Hoxc8^{tm2.1(cre)Mrc}/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal spinal cord dorsal horn morphology	J:162102
	normal behavior/neurological phenotype	J:162102
	increased thermal nociceptive threshold	J:162102
Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc}/Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc} Tg(Tek-cre)1Arnd/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * DBA/2	normal behavior/neurological phenotype	J:162102
	focal hair loss	J:162102
	increased grooming behavior	J:162102
	normal nervous system phenotype	J:162102
Hoxb8^{tm4.1(cre/Esr1)Mrc}/Hoxb8^{tm4.1(cre/Esr1)Mrc} involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	skin lesions	J:162102

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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