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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hoxc4
homeobox C4
MGI:96195
27 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hoxc4tm1Hsu/Hoxc4+
involves: 129S/SvEv * A/J 		abnormal rib development J:31635
abnormal thoracic vertebrae morphology J:31635
xiphoid process foramen J:31635
Hoxc4tm1Hsu/Hoxc4tm1Hsu
involves: 129S/SvEv * A/J 		abnormal rib development J:31635
abnormal sternocostal joint morphology J:31635
abnormal thoracic vertebrae morphology J:31635
normal behavior/neurological phenotype J:31635
increased rib number J:31635
increased sternebra number J:31635
normal nervous system phenotype J:31635
normal skeleton phenotype J:31635
xiphoid process foramen J:31635
Hoxc4tm1Mrc/Hoxc4+
involves: 129S7/SvEvBrd * C57BL/6 		abnormal sternocostal joint morphology J:34198
abnormal thoracic vertebrae morphology J:34198
thoracic vertebral transformation J:34198
Hoxc4tm1Mrc/Hoxc4tm1Mrc
involves: 129S7/SvEvBrd * C57BL/6 		abnormal esophageal smooth muscle morphology J:34198
abnormal sternocostal joint morphology J:34198
abnormal thoracic vertebrae morphology J:34198
absent gastric milk in neonates J:34198
postnatal lethality, incomplete penetrance J:34198
premature death J:34198
short ribs J:34198
sternum hypoplasia J:34198
thoracic vertebral transformation J:34198
Hoxc4tm2.1Mrc/Hoxc4tm2.1Mrc
involves: 129S/SvEv * C57BL/6 		abnormal class switch recombination J:148278
abnormal somatic hypermutation frequency J:148278
decreased IgA level J:148278
decreased IgE level J:148278
decreased IgG1 level J:148278
decreased IgG2a level J:148278
decreased IgG2b level J:148278
decreased IgG3 level J:148278
decreased IgM level J:148278
normal immune system phenotype J:148278
normal mortality/aging J:148278
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory