Hoxd Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hoxd
homeobox D cluster
MGI:96200

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Del(2Hoxd11-Hoxd13)29Ddu/Hoxd^tm3Ddu involves: 129S2/SvPas * C57BL/6 * SJL	abnormal digit morphology	J:47900
	polydactyly	J:47900
Dp(2Hoxd8-Hoxd9)2Ddu/Hoxd^{tm21(Hoxd11)Ddu} involves: 129S2/SvPas	normal renal/urinary system phenotype	J:131874
Hoxa11^tm1Ssp/Hoxa11⁺ Hoxd^tm3Ddu/Hoxd⁺ involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL	normal skeleton phenotype	J:47900
Hoxa11^tm1Ssp/Hoxa11⁺ Hoxd^tm3Ddu/Hoxd^tm3Ddu involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL	abnormal fibula morphology	J:47900
	abnormal radius morphology	J:47900
	abnormal tibia morphology	J:47900
	abnormal ulna morphology	J:47900
Hoxa11^tm1Ssp/Hoxa11^tm1Ssp Hoxd^tm3Ddu/Hoxd^tm3Ddu involves: 129S2/SvPas * C57BL/6 * CF-1 * SJL	abnormal fibula morphology	J:47900
	abnormal tibia morphology	J:47900
	increased diameter of fibula	J:47900
	increased diameter of radius	J:47900
	increased diameter of tibia	J:47900
	increased diameter of ulna	J:47900
Hoxa^tm1.1Ssp/Hoxa⁺ Hoxd^tm1.1Ssp/Hoxd⁺ involves: 129 * CD-1	abnormal internal female genitalia morphology	J:198638
	abnormal vas deferens morphology	J:198638
	decreased litter size	J:198638
	female infertility	J:198638
	reduced female fertility	J:198638
Hoxa^tm1.1Ssp/Hoxa⁺ Hoxd^tm1.1Ssp/Hoxd^tm1.1Ssp involves: 129 * CD-1	abnormal cauda epididymis morphology	J:198638
	abnormal testis morphology	J:198638
	abnormal uterus morphology	J:198638
	abnormal vas deferens morphology	J:198638
	female infertility	J:198638
	small epididymis	J:198638
	thin myometrium	J:198638
	thin uterus	J:198638
	unilateral cryptorchism	J:198638
Hoxa^tm1.1Ssp/Hoxa^tm1.1Ssp Hoxd^tm1.1Ssp/Hoxd⁺ involves: 129 * CD-1	abnormal cauda epididymis morphology	J:198638
	abnormal uterus morphology	J:198638
	abnormal vas deferens morphology	J:198638
	female infertility	J:198638
	male infertility	J:198638
	small epididymis	J:198638
	thin myometrium	J:198638
	thin uterus	J:198638
Hoxa^tm1.1Ssp/Hoxa^tm1.1Ssp Hoxd^tm1.1Ssp/Hoxd^tm1.1Ssp involves: 129 * CD-1	neonatal lethality, complete penetrance	J:198638
Hoxd^tm11Ddu/Hoxd⁺ Tg(Hoxd9/lacZ/neo)4Ddu/0 involves: 129S2/SvPas	abnormal digit morphology	J:82850
	abnormal metatarsal bone morphology	J:82850
	abnormal phalanx morphology	J:82850

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24