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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hr
lysine demethylase and nuclear receptor corepressor
MGI:96223
128 phenotypes from 29 alleles in 29 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hrba/Hrba
Not Specified 		abnormal coat appearance J:13067
abnormal nipple development J:13067
abnormal skin condition J:13067
absent mammary gland J:13067
decreased body weight J:13067
decreased nipple number J:13067
hairless J:13067, J:64270
loss of vibrissae J:13067
sparse hair J:13067
thick skin J:13067
translucent skin J:13067
wrinkled skin J:13067
Hrbldy/Hrbldy
C57BL/6J-Hrbldy/Nwu 		alopecia J:83419
wrinkled skin J:83419
Hrem1(IMPC)H/Hrem1(IMPC)H
C57BL/6NTac-Hrem1(IMPC)H/H 		abnormal coat/ hair morphology J:211773
abnormal vibrissa morphology J:211773
absent vibrissae J:211773
decreased circulating alkaline phosphatase level J:211773
decreased circulating amylase level J:211773
decreased circulating cholesterol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
HrHp/Hr+
BALB/cJ-HrHp 		abnormal epidermal layer morphology J:150720
abnormal vibrissa follicle morphology J:150720
abnormal vibrissa morphology J:150720
abnormal vibrissa number J:150720
alopecia J:150720
epidermal cyst J:150720
short hair J:150720
sparse hair J:150720
wavy vibrissae J:150720
wrinkled skin J:150720
HrHp/HrHp
BALB/cJ-HrHp 		abnormal epidermal layer morphology J:150720
abnormal hair cycle J:150720
abnormal hair follicle dermal papilla morphology J:150720
abnormal hair follicle inner root sheath morphology J:150720
abnormal hair follicle morphology J:150720
abnormal hair shaft morphology J:150720
abnormal vibrissa morphology J:150720
abnormal vibrissa number J:150720
alopecia J:150720
curly vibrissae J:150720
epidermal cyst J:150720
thin skin J:150720
wavy vibrissae J:150720
wrinkled skin J:150720
Hrhr+/Hrhr+
HRA/Skh 		normal integument phenotype J:9252
Hrhr-2Pas/Hrhr-2Pas
involves: BALB/c 		abnormal hair growth J:82809
hairless J:82809
Hrhr/Hrhr-3J
involves: MRL/MpJ 		abnormal hair growth J:78381
hairless J:78381
Hrhr/Hrhr
HRS/J 		absent linear vestibular evoked potential J:116914
decreased T cell number J:6087
decreased T cell proliferation J:6375
increased leukemia incidence J:5726, J:5908, J:24786
increased macrophage cell number J:150402
Hrhr/Hrhr
Not Specified 		abnormal dermis reticular layer morphology J:2409
abnormal mammary gland morphology J:2409
abnormal nursing J:2409
abnormal skin morphology J:2409
deformed nails J:2409
dermal cyst J:2409, J:14889
epidermal hyperplasia J:14940
hairless J:2405, J:2409
hyperkeratosis J:14940
sebaceous gland atrophy J:2409
Hrhr/Hrrh-2J
involves: BALB/cBy * C57BL/6By * HRS/J 		wrinkled skin J:27523
Hrm1Btlr/Hrm1Btlr
C57BL/6J-Hrm1Btlr 		hairless J:138686
normal hematopoietic system phenotype J:138686
normal immune system phenotype J:138686
long toenails J:138686
loose skin J:138686
wrinkled skin J:138686
Hrm1Enu/Hrm1Enu
BALB/cJ-Hrm1Enu 		abnormal epidermal layer morphology J:108173
abnormal epidermis stratum corneum morphology J:108173
acanthosis J:108173
alopecia J:108173
deformed nails J:108173
dermal cyst J:108173
granulomatous inflammation J:108173
loose skin J:108173
loss of vibrissae J:108173
Hrm2Btlr/Hrm2Btlr
C57BL/6J-Hrm2Btlr 		hairless J:145522
thick skin J:145522
wrinkled skin J:145522
HrM3Btlr/HrM3Btlr
C57BL/6J-HrM3Btlr 		alopecia J:179959
progressive hair loss J:179959
Hrm4Btlr/Hrm4Btlr
C57BL/6J-Hrm4Btlr 		abnormal skin adnexa physiology J:192585
alopecia J:192585
Hrm5Btlr/Hrm5Btlr
C57BL/6J-Hrm5Btlr 		alopecia J:218969
wrinkled skin J:218969
Hrm6Btlr/Hrm6Btlr
C57BL/6J-Hrm6Btlr 		alopecia J:264680
HrN/Hr+
involves: ORNL:STOCK Aw/a Oca2p 		abnormal coat appearance J:7103
abnormal hair growth J:7103
abnormal vibrissa morphology J:7103
curly vibrissae J:7103
shiny skin J:7103
short vibrissae J:7103
sparse hair J:7103
thin skin J:7103
HrN/Hrhr
involves: ORNL:STOCK Aw/a Oca2p 		abnormal coat appearance J:7103
abnormal skin condition J:7103
HrN/HrN
involves: ORNL:STOCK Aw/a Oca2p 		abnormal lactation J:7103
abnormal vibrissa morphology J:7103
hairless J:7103
short vibrissae J:7103
thin skin J:7103
wrinkled skin J:7103
Hrrh-7J/Hrrh
involves: C57BL/6J * HRS/J 		abnormal hair growth J:78474
Hrrh-8J/Hrrh-8J
B10.D2/nSnJ-Hrrh-8J 		abnormal hair cycle J:50909
abnormal skin appearance J:50909
absent hair follicle dermal papilla J:50909
alopecia J:50909
dermal cyst J:50909
dilated hair follicle infundibulum J:50909
Hrrh-10J/Hrrh-10J
C57BL/6J-Hrrh-10J/GrsrJ 		abnormal hair follicle morphology J:206787
decreased body size J:206787
dilated hair follicle J:206787
hairless J:206787
long toenails J:206787
preweaning lethality, incomplete penetrance J:206787
thick skin J:206787
wrinkled skin J:206787
Hrrh-bmh/Hrrh-bmh
involves: C57BL/6JRj * CBA/JRj 		abnormal hair follicle inner root sheath morphology J:89321
abnormal hair follicle morphology J:89321
abnormal hair follicle outer root sheath morphology J:89321
alopecia J:89321
dermal cyst J:89321
dilated hair follicle infundibulum J:89321
dilated piliary canal J:89321
normal immune system phenotype J:89321
Hrrh-Chr/Hrrh-Chr
Not Specified 		abnormal sebaceous gland morphology J:53633
decreased sebocyte cell number J:53633
dermal cyst J:53633
hairless J:53633
small sebaceous gland J:53633
Hrrh-R/Hrrh-R
involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El 		abnormal epidermis stratum granulosum morphology J:156542
abnormal hair follicle infundibulum morphology J:156542
abnormal hair follicle morphology J:156542
abnormal nursing J:156542
abnormal vibrissa number J:156542
decreased thymus weight J:156542
dermal cyst J:156542
dilated hair follicle infundibulum J:156542
epidermis stratum granulosum hyperplasia J:156542
hypergranulosis J:156542
long toenails J:156542
progressive hair loss J:156542
wrinkled skin J:156542
Hrrh-Y/Hrrh-Y
involves: B10.R109/Y * C57BL/10SnY 		abnormal skin morphology J:53634
decreased ovulation rate J:53634
dermal cyst J:53634
female infertility J:53634
hair follicle degeneration J:53634
hairless J:53634
Hrrh/Hrrh
involves: FVB/N 		decreased white adipose tissue amount J:192868
increased body weight J:192868
progressive hair loss J:192868
thick skin J:192868
wrinkled skin J:192868
Hrrh/Hrrh
Not Specified 		abnormal eyelid margin morphology J:16021
abnormal eyelid morphology J:16021
abnormal forehead morphology J:13057
abnormal lactation J:13057
abnormal Meibomian gland acinus morphology J:16021
abnormal Meibomian gland morphology J:16021
abnormal piliary canal morphology J:13057
abnormal sebaceous gland morphology J:16021
deformed nails J:13057
dilated hair follicle J:21692
epidermal cyst J:13008, J:14940
eye inflammation J:16021
hairless J:13057
hyperkeratosis J:13057
long toenails J:13057
loss of eyelid cilia J:16021
Meibomian gland atrophy J:16021
Meibomian gland cyst J:16021
progressive hair loss J:13057
skin ridges J:13057
thick epidermis J:14940
thick eyelids J:16021
wrinkled skin J:13057
Hrrh/Hrrh
RHJ/LeJ 		abnormal colon morphology J:57947
abnormal intestinal mucosa morphology J:57947
absent cochlear hair cell stereocilia J:57947
cochlear ganglion hypoplasia J:57947
decreased cochlear inner hair cell number J:57947
decreased cochlear outer hair cell number J:57947
decreased small intestinal villus height J:57947
thin retina ganglion layer J:57947
thin retina inner plexiform layer J:57947
thymus atrophy J:57947
Hrrhsl/Hrrhsl
involves: BALB/c 		abnormal dermal layer morphology J:98859
abnormal hair follicle morphology J:98859
abnormal keratinocyte differentiation J:98859
abnormal nursing J:98859
abnormal skin morphology J:98859
abnormal vibrissa morphology J:92362
alopecia J:98859
dermal cyst J:98859
flaky skin J:98859
hyperkeratosis J:98859
long toenails J:98859
loose skin J:98859
premature death J:98859
thick skin J:98859
thymus atrophy J:98859
wrinkled skin J:98859
HrTg5053Mm/HrTg5053Mm
involves: C3H/He * C57BL/6J 		abnormal skin condition J:15642
epidermal cyst J:15642
hair follicle degeneration J:15642
progressive hair loss J:15642
skin lesions J:15642
thick skin J:15642
wrinkled skin J:15642
Hrtm1Cct/Hrtm1Cct
involves: 129 		abnormal skin morphology J:102493
alopecia J:102493
Hrtm1Cct/Hrtm1Cct
involves: 129/Sv * C57BL/6 		abnormal skin morphology J:92053
alopecia J:92053
dermal cyst J:92053
dilated piliary canal J:92053
skin hyperplasia J:92053
wrinkled skin J:92053
HrUSP/HrUSP
either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2) 		abnormal dermal layer morphology J:101827
abnormal hair follicle morphology J:21316
abnormal hepatocyte morphology J:21316
abnormal immunoglobulin level J:21316
abnormal lymph node secondary follicle morphology J:21316
abnormal skin condition J:21316, J:101827
abnormal skin morphology J:101827
abnormal thymus involution J:21316
alopecia J:21316, J:101827
decreased IgM level J:21316
dermal cyst J:21316, J:101827
dilated hair follicle J:101827
enlarged inguinal lymph nodes J:21316
enlarged popliteal lymph nodes J:21316
glomerulonephritis J:21316
hair follicle degeneration J:101827
hyperkeratosis J:101827
increased IgG level J:21316
increased susceptibility to autoimmune disorder J:21316
long toenails J:21316, J:101827
lymph node inflammation J:21316
lymph node medullary cord hyperplasia J:21316
thick dermal layer J:101827
thick skin J:21316, J:101827
thin hypodermis J:101827
thymus cortex atrophy J:21316
wrinkled skin J:21316, J:101827
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory