About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hr
lysine demethylase and nuclear receptor corepressor
MGI:96223
128 phenotypes from 29 alleles in 29 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Hrba/Hrba
Not Specified 		abnormal coat appearance J:13067
abnormal nipple development J:13067
abnormal skin condition J:13067
absent mammary gland J:13067
decreased body weight J:13067
decreased nipple number J:13067
hairless J:13067, J:64270
loss of vibrissae J:13067
sparse hair J:13067
thick skin J:13067
translucent skin J:13067
wrinkled skin J:13067
Hrbldy/Hrbldy
C57BL/6J-Hrbldy/Nwu 		alopecia J:83419
wrinkled skin J:83419
Hrem1(IMPC)H/Hrem1(IMPC)H
C57BL/6NTac-Hrem1(IMPC)H/H 		abnormal coat/ hair morphology J:211773
abnormal vibrissa morphology J:211773
absent vibrissae J:211773
decreased circulating alkaline phosphatase level J:211773
decreased circulating amylase level J:211773
decreased circulating cholesterol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased lymphocyte cell number J:211773
increased neutrophil cell number J:211773
HrHp/Hr+
BALB/cJ-HrHp 		abnormal epidermal layer morphology J:150720
abnormal vibrissa follicle morphology J:150720
abnormal vibrissa morphology J:150720
abnormal vibrissa number J:150720
alopecia J:150720
epidermal cyst J:150720
short hair J:150720
sparse hair J:150720
wavy vibrissae J:150720
wrinkled skin J:150720
HrHp/HrHp
BALB/cJ-HrHp 		abnormal epidermal layer morphology J:150720
abnormal hair cycle J:150720
abnormal hair follicle dermal papilla morphology J:150720
abnormal hair follicle inner root sheath morphology J:150720
abnormal hair follicle morphology J:150720
abnormal hair shaft morphology J:150720
abnormal vibrissa morphology J:150720
abnormal vibrissa number J:150720
alopecia J:150720
curly vibrissae J:150720
epidermal cyst J:150720
thin skin J:150720
wavy vibrissae J:150720
wrinkled skin J:150720
Hrhr+/Hrhr+
HRA/Skh 		normal integument phenotype J:9252
Hrhr-2Pas/Hrhr-2Pas
involves: BALB/c 		abnormal hair growth J:82809
hairless J:82809
Hrhr/Hrhr-3J
involves: MRL/MpJ 		abnormal hair growth J:78381
hairless J:78381
Hrhr/Hrhr
HRS/J 		absent linear vestibular evoked potential J:116914
decreased T cell number J:6087
decreased T cell proliferation J:6375
increased leukemia incidence J:5726, J:5908, J:24786
increased macrophage cell number J:150402
Hrhr/Hrhr
Not Specified 		abnormal dermis reticular layer morphology J:2409
abnormal mammary gland morphology J:2409
abnormal nursing J:2409
abnormal skin morphology J:2409
deformed nails J:2409
dermal cyst J:2409, J:14889
epidermal hyperplasia J:14940
hairless J:2405, J:2409
hyperkeratosis J:14940
sebaceous gland atrophy J:2409
Hrhr/Hrrh-2J
involves: BALB/cBy * C57BL/6By * HRS/J 		wrinkled skin J:27523
Hrm1Btlr/Hrm1Btlr
C57BL/6J-Hrm1Btlr 		hairless J:138686
normal hematopoietic system phenotype J:138686
normal immune system phenotype J:138686
long toenails J:138686
loose skin J:138686
wrinkled skin J:138686
Hrm1Enu/Hrm1Enu
BALB/cJ-Hrm1Enu 		abnormal epidermal layer morphology J:108173
abnormal epidermis stratum corneum morphology J:108173
acanthosis J:108173
alopecia J:108173
deformed nails J:108173
dermal cyst J:108173
granulomatous inflammation J:108173
loose skin J:108173
loss of vibrissae J:108173
Hrm2Btlr/Hrm2Btlr
C57BL/6J-Hrm2Btlr 		hairless J:145522
thick skin J:145522
wrinkled skin J:145522
HrM3Btlr/HrM3Btlr
C57BL/6J-HrM3Btlr 		alopecia J:179959
progressive hair loss J:179959
Hrm4Btlr/Hrm4Btlr
C57BL/6J-Hrm4Btlr 		abnormal skin adnexa physiology J:192585
alopecia J:192585
Hrm5Btlr/Hrm5Btlr
C57BL/6J-Hrm5Btlr 		alopecia J:218969
wrinkled skin J:218969
Hrm6Btlr/Hrm6Btlr
C57BL/6J-Hrm6Btlr 		alopecia J:264680
HrN/Hr+
involves: ORNL:STOCK Aw/a Oca2p 		abnormal coat appearance J:7103
abnormal hair growth J:7103
abnormal vibrissa morphology J:7103
curly vibrissae J:7103
shiny skin J:7103
short vibrissae J:7103
sparse hair J:7103
thin skin J:7103
HrN/Hrhr
involves: ORNL:STOCK Aw/a Oca2p 		abnormal coat appearance J:7103
abnormal skin condition J:7103
HrN/HrN
involves: ORNL:STOCK Aw/a Oca2p 		abnormal lactation J:7103
abnormal vibrissa morphology J:7103
hairless J:7103
short vibrissae J:7103
thin skin J:7103
wrinkled skin J:7103
Hrrh-7J/Hrrh
involves: C57BL/6J * HRS/J 		abnormal hair growth J:78474
Hrrh-8J/Hrrh-8J
B10.D2/nSnJ-Hrrh-8J 		abnormal hair cycle J:50909
abnormal skin appearance J:50909
absent hair follicle dermal papilla J:50909
alopecia J:50909
dermal cyst J:50909
dilated hair follicle infundibulum J:50909
Hrrh-10J/Hrrh-10J
C57BL/6J-Hrrh-10J/GrsrJ 		abnormal hair follicle morphology J:206787
decreased body size J:206787
dilated hair follicle J:206787
hairless J:206787
long toenails J:206787
preweaning lethality, incomplete penetrance J:206787
thick skin J:206787
wrinkled skin J:206787
Hrrh-bmh/Hrrh-bmh
involves: C57BL/6JRj * CBA/JRj 		abnormal hair follicle inner root sheath morphology J:89321
abnormal hair follicle morphology J:89321
abnormal hair follicle outer root sheath morphology J:89321
alopecia J:89321
dermal cyst J:89321
dilated hair follicle infundibulum J:89321
dilated piliary canal J:89321
normal immune system phenotype J:89321
Hrrh-Chr/Hrrh-Chr
Not Specified 		abnormal sebaceous gland morphology J:53633
decreased sebocyte cell number J:53633
dermal cyst J:53633
hairless J:53633
small sebaceous gland J:53633
Hrrh-R/Hrrh-R
involves: 101 * C3H/Rl * C57BL/RlEl * C57BL/10Rl * SEC/El 		abnormal epidermis stratum granulosum morphology J:156542
abnormal hair follicle infundibulum morphology J:156542
abnormal hair follicle morphology J:156542
abnormal nursing J:156542
abnormal vibrissa number J:156542
decreased thymus weight J:156542
dermal cyst J:156542
dilated hair follicle infundibulum J:156542
epidermis stratum granulosum hyperplasia J:156542
hypergranulosis J:156542
long toenails J:156542
progressive hair loss J:156542
wrinkled skin J:156542
Hrrh-Y/Hrrh-Y
involves: B10.R109/Y * C57BL/10SnY 		abnormal skin morphology J:53634
decreased ovulation rate J:53634
dermal cyst J:53634
female infertility J:53634
hair follicle degeneration J:53634
hairless J:53634
Hrrh/Hrrh
involves: FVB/N 		decreased white adipose tissue amount J:192868
increased body weight J:192868
progressive hair loss J:192868
thick skin J:192868
wrinkled skin J:192868
Hrrh/Hrrh
Not Specified 		abnormal eyelid margin morphology J:16021
abnormal eyelid morphology J:16021
abnormal forehead morphology J:13057
abnormal lactation J:13057
abnormal Meibomian gland acinus morphology J:16021
abnormal Meibomian gland morphology J:16021
abnormal piliary canal morphology J:13057
abnormal sebaceous gland morphology J:16021
deformed nails J:13057
dilated hair follicle J:21692
epidermal cyst J:13008, J:14940
eye inflammation J:16021
hairless J:13057
hyperkeratosis J:13057
long toenails J:13057
loss of eyelid cilia J:16021
Meibomian gland atrophy J:16021
Meibomian gland cyst J:16021
progressive hair loss J:13057
skin ridges J:13057
thick epidermis J:14940
thick eyelids J:16021
wrinkled skin J:13057
Hrrh/Hrrh
RHJ/LeJ 		abnormal colon morphology J:57947
abnormal intestinal mucosa morphology J:57947
absent cochlear hair cell stereocilia J:57947
cochlear ganglion hypoplasia J:57947
decreased cochlear inner hair cell number J:57947
decreased cochlear outer hair cell number J:57947
decreased small intestinal villus height J:57947
thin retina ganglion layer J:57947
thin retina inner plexiform layer J:57947
thymus atrophy J:57947
Hrrhsl/Hrrhsl
involves: BALB/c 		abnormal dermal layer morphology J:98859
abnormal hair follicle morphology J:98859
abnormal keratinocyte differentiation J:98859
abnormal nursing J:98859
abnormal skin morphology J:98859
abnormal vibrissa morphology J:92362
alopecia J:98859
dermal cyst J:98859
flaky skin J:98859
hyperkeratosis J:98859
long toenails J:98859
loose skin J:98859
premature death J:98859
thick skin J:98859
thymus atrophy J:98859
wrinkled skin J:98859
HrTg5053Mm/HrTg5053Mm
involves: C3H/He * C57BL/6J 		abnormal skin condition J:15642
epidermal cyst J:15642
hair follicle degeneration J:15642
progressive hair loss J:15642
skin lesions J:15642
thick skin J:15642
wrinkled skin J:15642
Hrtm1Cct/Hrtm1Cct
involves: 129 		abnormal skin morphology J:102493
alopecia J:102493
Hrtm1Cct/Hrtm1Cct
involves: 129/Sv * C57BL/6 		abnormal skin morphology J:92053
alopecia J:92053
dermal cyst J:92053
dilated piliary canal J:92053
skin hyperplasia J:92053
wrinkled skin J:92053
HrUSP/HrUSP
either: (involves: A/J * BALB/c) or (involves: BALB/c * C57BL/6) or (involves: BALB/c * DBA/2) 		abnormal dermal layer morphology J:101827
abnormal hair follicle morphology J:21316
abnormal hepatocyte morphology J:21316
abnormal immunoglobulin level J:21316
abnormal lymph node secondary follicle morphology J:21316
abnormal skin condition J:21316, J:101827
abnormal skin morphology J:101827
abnormal thymus involution J:21316
alopecia J:21316, J:101827
decreased IgM level J:21316
dermal cyst J:21316, J:101827
dilated hair follicle J:101827
enlarged inguinal lymph nodes J:21316
enlarged popliteal lymph nodes J:21316
glomerulonephritis J:21316
hair follicle degeneration J:101827
hyperkeratosis J:101827
increased IgG level J:21316
increased susceptibility to autoimmune disorder J:21316
long toenails J:21316, J:101827
lymph node inflammation J:21316
lymph node medullary cord hyperplasia J:21316
thick dermal layer J:101827
thick skin J:21316, J:101827
thin hypodermis J:101827
thymus cortex atrophy J:21316
wrinkled skin J:21316, J:101827
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory