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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Hras
Harvey rat sarcoma virus oncogene
MGI:96224
70 phenotypes from 9 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hrastm1Esn/Hrastm1Esn
involves: 129X1/SvJ * C57BL/6N 		no abnormal phenotype detected J:67374
Hrastm1Grnt/Hrastm1Grnt
involves: 129P2/OlaHsd 		normal nervous system phenotype J:98903
Hrastm1Jaf/Hras+
Tg(CAG-cre)13Miya/0
involves: 129S6/SvEvTac * Black Swiss * C57BL/6 		abnormal ameloblast differentiation J:204891
abnormal ameloblast morphology J:148393, J:204891
abnormal cervical loop morphology J:204891
abnormal enamel mineralization J:148393, J:204891
abnormal enamel morphology J:204891
abnormal enamel rod pattern J:204891
abnormal stellate reticulum morphology J:204891
abnormal stratum intermedium morphology J:204891
abnormal suckling behavior J:148393
abnormal tooth development J:204891
absent enamel J:204891
cardiac fibrosis J:148393
deviated nasal septum J:148393
domed cranium J:148393
increased hemangiosarcoma incidence J:148393
increased papilloma incidence J:148393
increased skin papilloma incidence J:148393
increased stomach tumor incidence J:148393
jaw cyst J:204891
malocclusion J:148393
postnatal growth retardation J:148393
postnatal lethality, incomplete penetrance J:148393
premature death J:148393
Hrastm1Jaf/Hrastm1Jaf
Tg(TPO-cre)1Shk/0
involves: 129S6/SvEvTac * FVB/NCr 		normal neoplasm J:231492
Hrastm1Jaf/?
Tg(TPO-cre)1Shk/0
involves: 129S6/SvEvTac * FVB/NCr 		normal endocrine/exocrine gland phenotype J:168249
normal neoplasm J:168249
Hrastm1Mok/Hrastm1Mok
involves: 129S/SvEv * C57BL/6 * DBA/2 		chylous ascites J:159024
decreased incidence of tumors by chemical induction J:62962
Hrastm1Rak/Hras+
B6.129S4-Hrastm1Rak 		no abnormal phenotype detected J:94077
Hrastm1Xbr/Hrastm1Xbr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:137729
Hrastm2Xbr/Hrastm2Xbr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N 		abnormal aorta tunica media morphology J:137729
abnormal blood vessel morphology J:137729
abnormal branching of the mammary ductal tree J:137729
abnormal cranium morphology J:137729
abnormal facial morphology J:137729
abnormal frontal bone morphology J:137729
abnormal heart morphology J:137729
abnormal lip morphology J:137729
abnormal mammary gland development J:137729
abnormal vibrissa follicle morphology J:137729
normal cardiovascular system phenotype J:137729
choanal stenosis J:137729
decreased urine creatinine level J:137729
depressed nasal bridge J:137729
enlarged aortic valve J:137729
heart left ventricle hypertrophy J:137729
heart right ventricle hypertrophy J:137729
hypertension J:137729
increased circulating angiotensin II level J:137729
increased heart atrium size J:137729
increased heart ventricle size J:137729
increased mammary adenocarcinoma incidence J:137729
increased systemic arterial blood pressure J:137729
increased systemic arterial diastolic blood pressure J:137729
increased systemic arterial systolic blood pressure J:137729
mammary gland hyperplasia J:137729
normal neoplasm J:137729
renal fibrosis J:137729
normal renal/urinary system phenotype J:137729
normal respiratory system phenotype J:137729
short maxilla J:137729
short nasal bridge J:137729
short premaxilla J:137729
short zygomatic bone J:137729
Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi/0
Tg(Flt4-cre)44Ichi/0
involves: 129P2/OlaHsd * C57BL/6J 		lymphatic vessel hyperplasia J:159024
Tg(CAG-Bgeo,-Hras1,-EGFP)#Ichi/0
Tg(Tek-cre)12Flv/0
involves: 129P2/OlaHsd * C3H * C57BL/6 		normal cardiovascular system phenotype J:159024
edema J:159024
lethality throughout fetal growth and development, complete penetrance J:159024
lymphatic vessel hyperplasia J:159024
Tg(GFAP-Hras1)2Agu/0
involves: 129S1/Sv * 129X1/SvJ * ICR 		increased astrocytoma incidence J:69129
premature death J:69129
Tg(GFAP-Hras1)2Agu/Tg(GFAP-Hras1)2Agu
involves: 129S1/Sv * 129X1/SvJ * ICR 		abnormal astrocyte morphology J:69129
ataxia J:69129
hydrocephaly J:69129
increased astrocytoma incidence J:69129
postnatal growth retardation J:69129
premature death J:69129
trisomy J:69129
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory