Hsf1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hsf1
heat shock factor 1
MGI:96238

33 phenotypes from 5 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hsf1^{tm1.1(KOMP)Vlcg}/Hsf1⁺ C57BL/6N-Hsf1^{tm1.1(KOMP)Vlcg}/J	abnormal retina morphology	J:211773
	abnormal sleep behavior	J:211773
	decreased circulating glucose level	J:211773
Hsf1^{tm1.1(KOMP)Vlcg}/Hsf1^{tm1.1(KOMP)Vlcg} C57BL/6N-Hsf1^{tm1.1(KOMP)Vlcg}/J	abnormal embryo size	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Hsf1^tm1.1Echr/Hsf1^tm1.1Echr Tg(Zp3-cre)93Knw/0 involves: 129S2/SvPas * C57BL/6J	abnormal female meiosis	J:175085
	abnormal meiotic spindle assembly checkpoint	J:175085
Hsf1^tm1Anak/Hsf1^tm1Anak involves: C57BL/6 * CBA * ICR	abnormal spermatogenesis	J:89846
Hsf1^tm1Anak/Hsf1^tm1Anak involves: C57BL/6 * CBA * ICR	normal reproductive system phenotype	J:89846
Hsf1^tm1Anak/Hsf1^tm1Anak involves: ICR	normal vision/eye phenotype	J:93301
Hsf1^tm1Ijb/Hsf1^tm1Ijb 129.129S6-Hsf1^tm1Ijb	abnormal astrocyte morphology	J:93600
	abnormal brain morphology	J:93600
	abnormal brain ventricle morphology	J:93600
	abnormal brain white matter morphology	J:93600
	abnormal corpus callosum morphology	J:93600
	abnormal putamen morphology	J:93600
	abnormal striatum morphology	J:93600
	dilated lateral ventricle	J:93600
	dilated third ventricle	J:93600
Hsf1^tm1Ijb/Hsf1^tm1Ijb either: (involves: 129S6/SvEvTac * 129X1/SvJ) or (involves: 129S6/SvEvTac * BALB/c) or (involves: 129S6/SvEvTac * C57BL/6J) or (involves: 129S6/SvEvTac * ICR)	abnormal extraembryonic tissue morphology	J:58383
	abnormal placenta labyrinth morphology	J:58383
	decreased body weight	J:58383
	decreased spongiotrophoblast size	J:58383
	failure of zygotic cell division	J:65267
	female infertility	J:58383, J:65267
	increased susceptibility to bacterial infection	J:58383
	increased tumor necrosis factor secretion	J:58383
	postnatal growth retardation	J:58383
	prenatal lethality, incomplete penetrance	J:58383, J:73593
Hsf1^tm1Ijb/Hsf1^tm1Ijb involves: 129S6/SvEvTac	abnormal chromosomal synapsis	J:175085
	abnormal female meiosis	J:175085
	abnormal meiotic spindle assembly checkpoint	J:175085
	abnormal synaptonemal complex	J:175085
Hsf1^tm1Miv/Hsf1^tm1Miv involves: 129S2/SvPas * C57BL/6	abnormal cell death	J:88534
	decreased sensitivity to induced cell death	J:88534
	female infertility	J:88534

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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