Hsf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hsf2
heat shock factor 2
MGI:96239

34 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hsf2^{tm1b(KOMP)Wtsi}/Hsf2^{tm1b(KOMP)Wtsi} C57BL/6N-Hsf2^{tm1b(KOMP)Wtsi}/J	decreased circulating glucose level	J:211773
	decreased urine glucose level	J:211773
	increased circulating sodium level	J:211773
Hsf2^tm1Ijb/Hsf2^tm1Ijb either: (involves: 129S6/SvEvTac * 129X1/SvJ) or (involves: 129S6/SvEvTac * C57BL/6)	no abnormal phenotype detected	J:79910
Hsf2^tm1Miv/Hsf2^tm1Miv involves: 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal seminiferous tubule morphology	J:88035
	abnormal spermatogenesis	J:83730, J:88035
	collapsed brain ventricles	J:83730
	decreased litter size	J:83730
	decreased male germ cell number	J:88035
	decreased testis weight	J:88035
	dilated lateral ventricle	J:83730
	dilated third ventricle	J:83730
	intracerebral hemorrhage	J:83730
	oligozoospermia	J:83730, J:88035
	postnatal lethality, incomplete penetrance	J:83730
	prenatal lethality, incomplete penetrance	J:83730
	reduced female fertility	J:83730
	small testis	J:83730
Hsf2^tm1Mmr/Hsf2^tm1Mmr involves: 129S2/SvPas * C57BL/6	abnormal female germ cell morphology	J:76942
	abnormal male germ cell apoptosis	J:76942
	abnormal male meiosis	J:76942
	abnormal ovarian follicle morphology	J:76942
	abnormal spermatogenesis	J:76942
	abnormal synaptonemal complex	J:76942
	absent corpus luteum	J:76942
	decreased epididymis weight	J:76942
	decreased litter size	J:76942
	decreased mature ovarian follicle number	J:76942
	decreased oocyte number	J:76942
	decreased testis weight	J:76942
	enlarged lateral ventricles	J:76942
	enlarged third ventricle	J:76942
	maternal effect	J:76942
	oligozoospermia	J:76942
	ovarian follicular cyst	J:76942
	ovary hemorrhage	J:76942
	reduced female fertility	J:76942
	small hippocampus	J:76942
	small seminiferous tubules	J:76942
	small testis	J:76942

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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