Htr1b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Htr1b
5-hydroxytryptamine (serotonin) receptor 1B
MGI:96274

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Creb1^tm3Gsc/Creb1⁺ Htr1b^tm1Rhn/Htr1b^tm1Rhn Tg(Col1a1-cre)1Kry/0 involves: 129P2/OlaHsd * 129S2/SvPas * FVB/N	normal skeleton phenotype	J:146078
Htr1b^tm1Rhn/Htr1b⁺ Lrp5^tm1Kry/Lrp5^tm1Kry involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ	normal skeleton phenotype	J:146078
Htr1b^tm1Rhn/Htr1b⁺ Tph1^tm1Kry/Tph1⁺ Tg(Vil1-cre)20Syr/0 involves: 129S2/SvPas * C57BL/6 * DBA/2	increased bone mass	J:146078
Htr1b^tm1Rhn/Htr1b^tm1Rhn Slc6a4^tm1Kpl/Slc6a4^tm1Kpl involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	abnormal heart valve morphology	J:121505
	cardiac fibrosis	J:121505
	decreased cardiac muscle contractility	J:121505
	dilated cardiomyopathy	J:121505
	heart valve hyperplasia	J:121505

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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