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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ica1
islet cell autoantigen 1
MGI:96391
14 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ica1tm1b(EUCOMM)Wtsi/Ica1tm1b(EUCOMM)Wtsi
C57BL/6N-Ica1tm1b(EUCOMM)Wtsi/Tcp 		abnormal cecum morphology J:211773
abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal spleen morphology J:211773
decreased locomotor activity J:211773
enlarged cecum J:211773
enlarged kidney J:211773
small spleen J:211773
Ica1tm1Mdos/Ica1tm1Mdos
involves: 129S1/Sv * 129X1/SvJ 		no abnormal phenotype detected J:83526
normal reproductive system phenotype J:233657
Ica1tm1Mdos/Ica1tm1Mdos
NOD.129-Ica1tm1Mdos 		abnormal glucose homeostasis J:83526
abnormal T cell physiology J:83526
decreased susceptibility to autoimmune diabetes J:83526
premature death J:83526
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory