Id1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Id1
inhibitor of DNA binding 1, HLH protein
MGI:96396

43 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Id1^tm1Xhsu/Id1^tm1Xhsu B6.129X1-Id1^tm1Xhsu	decreased hematopoietic stem cell number	J:144696
Id1^tm1Zhu/Id1⁺ involves: 129S1/Sv * 129S4/SvJaeSor	decreased metastatic potential	J:86480
	decreased tumor growth/size	J:86480
	tumor regression	J:86480
Id1^tm1Zhu/Id1^tm1Zhu either: 129/Sv-Id1^tm1Zhu or (involves: 129S1/Sv * C57BL/6)	normal cardiovascular system phenotype	J:44278
	normal digestive/alimentary phenotype	J:44278
	normal endocrine/exocrine gland phenotype	J:44278
	normal hematopoietic system phenotype	J:44278
	normal liver/biliary system phenotype	J:44278
	normal mortality/aging	J:44278
	normal muscle phenotype	J:44278
	normal nervous system phenotype	J:44278
	normal renal/urinary system phenotype	J:44278
	normal reproductive system phenotype	J:44278
Id1^tm1Zhu/Id1^tm1Zhu involves: 129S1/Sv * C57BL/6	abnormal bone marrow cell morphology/development	J:119519
	abnormal bone marrow morphology	J:155384
	abnormal hematopoietic stem cell physiology	J:119519, J:155384
	abnormal myelopoiesis	J:155384
	abnormal osteoclast differentiation	J:155384
	decreased body size	J:155384
	decreased bone marrow cell number	J:119519
	decreased bone mineral content	J:155384
	decreased bone mineral density	J:155384
	decreased bone strength	J:155384
	decreased bone volume	J:155384
	decreased erythrocyte cell number	J:119519, J:155384
	decreased hematopoietic stem cell number	J:119519
	decreased lymphocyte cell number	J:119519
	decreased trabecular bone thickness	J:155384
	fragile skeleton	J:155384
	increased monocyte cell number	J:155384
	increased neutrophil cell number	J:155384
	increased osteoclast cell number	J:155384
	myeloid hyperplasia	J:155384
	osteoporosis	J:155384
	thrombocytopenia	J:155384
Id1^tm1Zhu/Id1^tm1Zhu involves: 129S1/Sv * C57BL/6J	abnormal lung morphology	J:125521
	decreased lung endothelial cell proliferation	J:125521
	increased lung endothelial cell apoptosis	J:125521
	increased vascular endothelial cell apoptosis	J:125521
	increased vascular permeability	J:125521
	pulmonary fibrosis	J:125521
Tg(Lck-Id1)28Xhsu/0 Not Specified	increased T cell derived lymphoma incidence	J:58607
Tg(Lck-Id1)28Xhsu/0 Not Specified	premature death	J:58607

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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