Id1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Id1
inhibitor of DNA binding 1, HLH protein
MGI:96396

43 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm1(cre/ERT2)Thl}/Gt(ROSA)26Sor⁺ Id1^tm3Bene/Id1^tm3Bene Id2^tm1Xdz/Id2^tm1Xdz Id3^tm1Zhu/Id3^tm1Zhu involves: 129S4/SvJaeSor * C57BL/6	premature neuronal precursor differentiation	J:185426
Id1^tm1Zhu/Id1⁺ Id3^tm1Zhu/Id3⁺ Twist1^tm1Bhr/Twist1⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd	premature cranial suture closure	J:108218
Id1^tm1Zhu/Id1⁺ Id3^tm1Zhu/Id3^tm1Zhu involves: 129S1/Sv * 129S4/SvJaeSor	abnormal middle ear morphology	J:311050
	abnormal tumor vascularization	J:86480
	conductive hearing loss	J:311050
	decreased distortion product otoacoustic emission amplitude	J:311050
	decreased metastatic potential	J:86480
	decreased tumor growth/size	J:86480
	increased or absent threshold for auditory brainstem response	J:311050
	increased susceptibility to otitis media	J:311050
	middle ear effusion	J:311050
	tumor regression	J:86480
Id1^tm1Zhu/Id1^tm1Zhu Id3^tm1Zhu/Id3⁺ involves: 129S1/Sv * 129S4/SvJaeSor	abnormal middle ear morphology	J:311050
	conductive hearing loss	J:311050
	decreased distortion product otoacoustic emission amplitude	J:311050
	increased or absent threshold for auditory brainstem response	J:311050
	increased susceptibility to otitis media	J:311050
	middle ear effusion	J:311050
	normal vision/eye phenotype	J:170418
Id1^tm1Zhu/Id1^tm1Zhu Id3^tm1Zhu/Id3⁺ Twist1^tm1Bhr/Twist1⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129S7/SvEvBrd	normal skeleton phenotype	J:108218
Id1^tm1Zhu/Id1^tm1Zhu Id3^tm1Zhu/Id3^tm1Zhu either: (involves: 129S1/Sv * 129S4/SvJaeSor) or (involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6)	preweaning lethality, complete penetrance	J:44278
Id1^tm1Zhu/Id1^tm1Zhu Id3^tm1Zhu/Id3^tm1Zhu involves: 129S1/Sv * 129S4/SvJaeSor	abnormal brain vasculature morphology	J:86480
	abnormal embryonic/fetal subventricular zone morphology	J:86480
	abnormal neuronal precursor proliferation	J:86480, J:170418
	abnormal retina development	J:170418
	decreased angiogenesis	J:86480
	decreased brain size	J:86480
	decreased embryo weight	J:86480
	embryonic lethality during organogenesis, complete penetrance	J:86480, J:170418
	intracranial hemorrhage	J:86480
	microphthalmia	J:170418
	premature neuronal precursor differentiation	J:86480
	retina hypoplasia	J:170418
	small lens	J:170418
Id1^tm1Zhu/Id1^tm1Zhu Tcf3^tm1Wein/Tcf3^tm1Wein involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6	abnormal thymus corticomedullary boundary morphology	J:44278
	absent B cells	J:44278
	arrested B cell differentiation	J:44278
	decreased lymphocyte cell number	J:44278
	increased T cell derived lymphoma incidence	J:44278
	intermingled spleen red and white pulp	J:44278
	neonatal lethality, incomplete penetrance	J:44278
	postnatal growth retardation	J:44278
	postnatal lethality, incomplete penetrance	J:44278
Id1^tm1Zhu/Id1^tm1Zhu Twist1^tm1Bhr/Twist1⁺ involves: 129S1/Sv * 129S7/SvEvBrd	premature cranial suture closure	J:108218
Id1^tm3Bene/Id1^tm3Bene Id2^tm1Xdz/Id2⁺ Id3^tm1Zhu/Id3^tm1Zhu Tg(Nes-cre)1Kln/0 involves: 129S4/SvJaeSor * C57BL/6 * SJL	normal nervous system phenotype	J:185426
Id1^tm3Bene/Id1^tm3Bene Id2^tm1Xdz/Id2^tm1Xdz Id3^tm1Zhu/Id3^tm1Zhu Tg(Nes-cre)1Kln/0 involves: 129S4/SvJaeSor * C57BL/6 * SJL	abnormal brain morphology	J:185426
	abnormal cell cycle	J:185426
	abnormal cortical ventricular zone morphology	J:185426
	abnormal neuron differentiation	J:185426
	abnormal neuronal precursor proliferation	J:185426
	enlarged brain ventricles	J:185426
	neonatal lethality, incomplete penetrance	J:185426
	premature neuronal precursor differentiation	J:185426
	thin external granule cell layer	J:185426

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