Ide Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ide
insulin degrading enzyme
MGI:96412

23 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ide^{Gt(OST132429)Lex}/Ide^{Gt(OST132429)Lex} involves: 129S5/SvEvBrd * C57BL/6-Tyr^c	amyloid beta deposits	J:82747
	hyperglycemia	J:82747
	impaired glucose tolerance	J:82747
	increased circulating insulin level	J:82747
Ide^{tm1a(EUCOMM)Wtsi}/Ide⁺ involves: C57BL/6N	decreased testis weight	J:274952
Ide^{tm1a(EUCOMM)Wtsi}/Ide⁺ involves: C57BL/6N	normal reproductive system phenotype	J:274952
Ide^{tm1a(EUCOMM)Wtsi}/Ide^{tm1a(EUCOMM)Wtsi} B6JTyr;B6N-Ide^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal cranium morphology	J:175295
	abnormal hair texture	J:175295
	abnormal incisor morphology	J:175295
	abnormal maxilla morphology	J:175295
	decreased body weight	J:175295
	decreased circulating alanine transaminase level	J:175295
	decreased circulating aspartate transaminase level	J:175295
	decreased circulating cholesterol level	J:175295
	decreased total body fat amount	J:175295
	increased circulating amylase level	J:175295
	increased heart weight	J:175295
Ide^{tm1a(EUCOMM)Wtsi}/Ide^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal mitochondrial ATP synthesis coupled electron transport	J:274952
	decreased testis weight	J:274952
	increased testis apoptosis	J:274952
	necrospermia	J:274952
	oxidative stress	J:274952
	normal reproductive system phenotype	J:274952
	small seminiferous tubules	J:274952
	teratozoospermia	J:274952

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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