About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
MGI:96413
30 phenotypes from 4 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Idh1tm1b(EUCOMM)Wtsi/Idh1tm1b(EUCOMM)Wtsi
C57BL/6N-Idh1tm1b(EUCOMM)Wtsi/Tcp 		decreased prepulse inhibition J:211773
preweaning lethality, incomplete penetrance J:211773
Idh1tm1Mak/Idh1tm1Mak
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/10 * CBA/Ca 		abnormal common lymphocyte progenitor cell morphology J:186700
abnormal common myeloid progenitor cell morphology J:186700
normal hematopoietic system phenotype J:186700
increased hematopoietic stem cell number J:186700
Idh1tm1Mak/Idh1tm1Mak
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6 		abnormal blood homeostasis J:186700
abnormal bone marrow cell morphology/development J:186700
abnormal bone marrow cell physiology J:186700
abnormal myeloblast morphology/development J:186700
abnormal spleen morphology J:186700
anemia J:186700
decreased B cell number J:186700
decreased bone marrow cell number J:186700
decreased CD4-positive, alpha-beta T cell number J:186700
decreased CD8-positive, alpha-beta T cell number J:186700
decreased common myeloid progenitor cell number J:186700
decreased hematocrit J:186700
decreased hemoglobin content J:186700
enlarged spleen J:186700
extramedullary hematopoiesis J:186700
normal hematopoietic system phenotype J:186700
increased CD4-positive, alpha-beta T cell number J:186700
increased hematopoietic stem cell number J:186700
Idh1tm2Mak/Idh1tm2Mak
Commd10Tg(Vav1-icre)A2Kio/Commd10+
involves: C57BL/6 * C57BL/10 * CBA/Ca 		abnormal common lymphocyte progenitor cell morphology J:186700
abnormal common myeloid progenitor cell morphology J:186700
normal hematopoietic system phenotype J:186700
increased hematopoietic stem cell number J:186700
Idh1tm2Mak/Idh1tm2Mak
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6 		abnormal blood homeostasis J:186700
abnormal bone marrow cell morphology/development J:186700
abnormal bone marrow cell physiology J:186700
abnormal myeloblast morphology/development J:186700
abnormal spleen morphology J:186700
anemia J:186700
decreased B cell number J:186700
decreased bone marrow cell number J:186700
decreased CD4-positive, alpha-beta T cell number J:186700
decreased CD8-positive, alpha-beta T cell number J:186700
decreased common myeloid progenitor cell number J:186700
decreased hematocrit J:186700
decreased hemoglobin content J:186700
enlarged spleen J:186700
extramedullary hematopoiesis J:186700
normal hematopoietic system phenotype J:186700
increased CD4-positive, alpha-beta T cell number J:186700
increased hematopoietic stem cell number J:186700
Idh1tm3Mak/Idh1+
Tg(Col2a1-cre)1Bhr/0
involves: C57BL/6 * SJL 		abnormal cartilage development J:220318
abnormal cartilage morphology J:220318
abnormal long bone epiphyseal plate morphology J:220318
abnormal tracheal cartilage morphology J:220318
decreased body size J:220318
pectus excavatum J:220318
postnatal lethality, complete penetrance J:220318
prenatal lethality, incomplete penetrance J:220318
Idh1tm3Mak/Idh1+
Tg(Col2a1-cre/ERT2)1Dic/0
involves: C57BL/6 		abnormal cartilage morphology J:220318
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory