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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Igf1r
insulin-like growth factor I receptor
MGI:96433
48 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Eef1a1tm1(Kras*)Arge/Eef1a1+
Igf1rtm2Arge/Igf1r+
Waptm1(cre)Arge/Wap+
involves: 129S1/Sv 		decreased tumor-free survival time J:146290
increased mammary gland tumor incidence J:146290
Eef1a1tm1(Kras*)Arge/Eef1a1+
Igf1rtm2Arge/Igf1rtm2Arge
Waptm1(cre)Arge/Wap+
involves: 129S1/Sv 		decreased tumor-free survival time J:146290
increased mammary gland tumor incidence J:146290
Gpc3tm1Arge/Gpc3tm1Arge
Igf1rtm1Arge/Igf1rtm1Arge
involves: 129S/SvEv * 129S1/Sv * C57BL/6J 		abnormal calcaneum morphology J:75054
abnormal hindlimb morphology J:75054
perinatal lethality, complete penetrance J:75054
Gpc3tm1Arge/Y
Igf1rtm1Arge/Igf1rtm1Arge
involves: 129S/SvEv * 129S1/Sv * C57BL/6J 		abnormal calcaneum morphology J:75054
abnormal hindlimb morphology J:75054
perinatal lethality, complete penetrance J:75054
Igf1tm1Arge/Igf1tm1Arge
Igf1rtm1Arge/Igf1rtm1Arge
either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1) 		decreased birth weight J:15108
delayed bone ossification J:15108
neonatal lethality, complete penetrance J:15108
respiratory failure J:15108
Igf1rtm1.1Mhz/Igf1r+
Insrtm1Khn/Insrtm1Khn
Tg(Ckmm-cre)5Khn/0
involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB 		abnormal breathing pattern J:118987
decreased heart left ventricle muscle contractility J:118987
decreased locomotor activity J:118987
normal homeostasis/metabolism phenotype J:118987
premature death J:118987
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz
Insrtm1Khn/Insr+
Tg(Ckmm-cre)5Khn/0
involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB 		normal cardiovascular system phenotype J:118987
normal growth/size/body region phenotype J:118987
normal homeostasis/metabolism phenotype J:118987
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz
Insrtm1Khn/Insrtm1Khn
involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB 		normal cardiovascular system phenotype J:118987
normal growth/size/body region phenotype J:118987
normal homeostasis/metabolism phenotype J:118987
Igf1rtm1.1Mhz/Igf1rtm1.1Mhz
Insrtm1Khn/Insrtm1Khn
Tg(Ckmm-cre)5Khn/0
involves: 129/Sv * 129S4/SvJae * C57BL/6 * FVB 		abnormal breathing pattern J:118987
abnormal heart left ventricle morphology J:118987
abnormal myocardial fiber morphology J:118987
cardiac interstitial fibrosis J:118987
congestive heart failure J:118987
decreased body weight J:118987
decreased heart left ventricle muscle contractility J:118987
decreased heart rate J:118987
decreased heart weight J:118987
decreased locomotor activity J:118987
decreased myocardial fiber size J:118987
dilated cardiomyopathy J:118987
normal homeostasis/metabolism phenotype J:118987
postnatal growth retardation J:118987
postnatal lethality, complete penetrance J:118987
small heart J:118987
thin interventricular septum J:118987
thin ventricular wall J:118987
Igf1rtm1.2Mhz/Igf1r+
Zfand2btm1Otin/Zfand2btm1Otin
involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 		normal hematopoietic system phenotype J:233169
normal neoplasm J:233169
Igf1rtm1Arge/Igf1r+
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129S/SvEv 		decreased survivor rate J:34584
increased birth weight J:34584
perinatal lethality, incomplete penetrance J:34584
Igf1rtm1Arge/Igf1r+
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129S/SvEv 		decreased survivor rate J:34584
increased birth weight J:34584
perinatal lethality, incomplete penetrance J:34584
Igf1rtm1Arge/Igf1r+
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129S/SvEv 		decreased survivor rate J:34584
increased birth weight J:34584
perinatal lethality, incomplete penetrance J:34584
Igf1rtm1Arge/Igf1r+
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129S/SvEv 		decreased survivor rate J:34584
increased birth weight J:34584
perinatal lethality, incomplete penetrance J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
involves: 129S/SvEv 		abnormal epidermal layer morphology J:15108
abnormal nervous system morphology J:15108
decreased birth weight J:15108
delayed bone ossification J:15108
maternal imprinting J:15108
neonatal lethality, complete penetrance J:15108
respiratory failure J:15108
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2+
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2tm1Rob/Igf2tm1Rob
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
small placenta J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
increased birth weight J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129S/SvEv 		abnormal maternal nurturing J:34584
decreased birth weight J:34584
decreased litter size J:34584
enlarged placenta J:34584
normal growth/size/body region phenotype J:34584
normal mortality/aging J:34584
slow postnatal weight gain J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm1Arge/Igf2r+
involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1 		decreased survivor rate J:34584
postnatal lethality, incomplete penetrance J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		increased birth weight J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129S/SvEv 		abnormal maternal nurturing J:34584
decreased litter size J:34584
enlarged placenta J:34584
normal growth/size/body region phenotype J:34584
normal mortality/aging J:34584
slow postnatal weight gain J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm1Arge/Igf2rtm1Arge
involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1 		decreased survivor rate J:34584
postnatal lethality, incomplete penetrance J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		decreased birth weight J:34584
increased birth weight J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129S/SvEv 		abnormal maternal nurturing J:34584
decreased birth weight J:34584
decreased litter size J:34584
enlarged placenta J:34584
normal growth/size/body region phenotype J:34584
normal mortality/aging J:34584
slow postnatal weight gain J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm2Arge/Igf2r+
involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1 		decreased survivor rate J:34584
postnatal lethality, incomplete penetrance J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv 		increased birth weight J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129S/SvEv 		abnormal maternal nurturing J:34584
decreased litter size J:34584
enlarged placenta J:34584
normal growth/size/body region phenotype J:34584
normal mortality/aging J:34584
slow postnatal weight gain J:34584
Igf1rtm1Arge/Igf1rtm1Arge
Igf2rtm2Arge/Igf2rtm2Arge
involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1 		decreased survivor rate J:34584
postnatal lethality, incomplete penetrance J:34586
Igf1rtm1Arge/Igf1rtm1Arge
Insrtm1Dac/Insr+
Insrrtm1Dac/Insrrtm1Dac
involves: 129S/SvEv * 129S1/Sv * 129S4/SvJae * C57BL/6J 		abnormal primary sex determination J:86618
primary sex reversal J:86618
Igf1rtm1Arge/Igf1rtm1Arge
Insrtm1Dac/Insrtm1Dac
involves: 129S/SvEv * 129S4/SvJae * C57BL/6J 		ovotestis J:86618
primary sex reversal J:86618
Igf1rtm1Arge/Igf1rtm1Arge
Insrtm1Dac/Insrtm1Dac
Insrrtm1Dac/Insrrtm1Dac
involves: 129S/SvEv * 129S1/Sv * 129S4/SvJae * C57BL/6J 		abnormal primary sex determination J:86618
primary sex reversal J:86618
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory