Igf2r Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Igf2r
insulin-like growth factor 2 receptor
MGI:96435

32 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Igf1r^tm1Arge/Igf1r⁺ Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1r^tm1Arge/Igf1r⁺ Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1r^tm1Arge/Igf1r⁺ Igf2r^tm2Arge/Igf2r⁺ involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1r^tm1Arge/Igf1r⁺ Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129S/SvEv	decreased survivor rate	J:34584
	increased birth weight	J:34584
	perinatal lethality, incomplete penetrance	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2^tm1Rob/Igf2⁺ Igf2r^tm2Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2^tm1Rob/Igf2⁺ Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased birth weight	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	increased birth weight	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm2Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm2Arge/Igf2r⁺ involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased birth weight	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm2Arge/Igf2r⁺ involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	increased birth weight	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129S/SvEv	abnormal maternal nurturing	J:34584
	decreased litter size	J:34584
	enlarged placenta	J:34584
	normal growth/size/body region phenotype	J:34584
	normal mortality/aging	J:34584
	slow postnatal weight gain	J:34584
Igf1r^tm1Arge/Igf1r^tm1Arge Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129S/SvEv * C57BL/6J * MF1	decreased survivor rate	J:34584
	postnatal lethality, incomplete penetrance	J:34586
Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
	small placenta	J:34584
Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased body size	J:34584
	normal mortality/aging	J:34584
	normal reproductive system phenotype	J:34584
Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr^tm1Hlk involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	abnormal gait	J:34584
	decreased body size	J:34584
	postnatal lethality, complete penetrance	J:34584
Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
	small placenta	J:34584
Igf2^tm1Rob/Igf2⁺ Igf2r^tm2Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
	small placenta	J:34584
Igf2^tm1Rob/Igf2⁺ Igf2r^tm2Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased body size	J:34584
	normal mortality/aging	J:34584
	normal reproductive system phenotype	J:34584
Igf2^tm1Rob/Igf2⁺ Igf2r^tm2Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr^tm1Hlk involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	abnormal gait	J:34584
	decreased body size	J:34584
	postnatal lethality, complete penetrance	J:34584
Igf2^tm1Rob/Igf2⁺ Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	increased birth weight	J:34584
	small placenta	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^{tm1.1(IGF2R)Arte}/Igf2r⁺ involves: C57BL/6J * C57BL/6NTac	normal growth/size/body region phenotype	J:197171
	normal mortality/aging	J:197171
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm1Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm1Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased body size	J:34584
	normal mortality/aging	J:34584
	normal reproductive system phenotype	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm1Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr^tm1Hlk involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	abnormal gait	J:34584
	decreased body size	J:34584
	postnatal lethality, complete penetrance	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm1Arge/Igf2r^tm1Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm2Arge/Igf2r⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm2Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr⁺ involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased body size	J:34584
	normal mortality/aging	J:34584
	normal reproductive system phenotype	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm2Arge/Igf2r⁺ M6pr^tm1Hlk/M6pr^tm1Hlk involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	abnormal gait	J:34584
	decreased body size	J:34584
	postnatal lethality, complete penetrance	J:34584
Igf2^tm1Rob/Igf2^tm1Rob Igf2r^tm2Arge/Igf2r^tm2Arge involves: 129/Sv * 129P2/OlaHsd * 129S/SvEv	decreased birth weight	J:34584
	small placenta	J:34584
Igf2r^{tm1.1(IGF2R)Arte}/Igf2r⁺ involves: C57BL/6J * C57BL/6NTac	abnormal uterine horn morphology	J:197171
	decreased litter size	J:197171
	dilated heart	J:197171
	dilated uterine horn	J:197171
	enlarged uterine horn	J:197171
	heart hemorrhage	J:197171
	increased body size	J:197171
	increased body weight	J:197171
	increased fetal weight	J:197171
	increased heart ventricle size	J:197171
	increased heart weight	J:197171
	increased placenta weight	J:197171
	preweaning lethality, incomplete penetrance	J:197171
Igf2r^{tm1.1(IGF2R)Arte}/Igf2r^{tm1.1(IGF2R)Arte} involves: C57BL/6J * C57BL/6NTac	normal growth/size/body region phenotype	J:197171
	normal mortality/aging	J:197171
Igf2r^{tm1.1(IGF2R)Arte}/Igf2r^tm2Wag involves: 129P2/OlaHsd * C57BL/6J * C57BL/6NTac	normal mortality/aging	J:197171
Igf2r^tm2Wag/Igf2r⁺ Del(17)T^hp/+ involves: 129/Sv * 129P2/OlaHsd * AKR/J * C57BL/6	abnormal tail morphology	J:68721
	decreased survivor rate	J:68721
	prenatal lethality, incomplete penetrance	J:68721
	normal reproductive system phenotype	J:68721
Rr28^tm1Tilg/Rr28⁺ Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Stw/Igf2r⁺ involves: 129S/SvEv * 129S1/Sv * C57BL/6J	increased fetal weight	J:77413
	neonatal lethality, complete penetrance	J:77413
	polydactyly	J:77413

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24