Igfbp3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Igfbp3
insulin-like growth factor binding protein 3
MGI:96438

21 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Igfbp3^{tm1b(KOMP)Wtsi}/Igfbp3^{tm1b(KOMP)Wtsi} C57BL/6N-Igfbp3^{tm1b(KOMP)Wtsi}/H	abnormal coat/hair pigmentation	J:211773
	short tibia	J:211773
	shortened ST segment	J:211773
	thick ventricular wall	J:211773
Igfbp3^tm1Jep/Igfbp3^tm1Jep involves: 129S/SvEv * C57BL/6J	abnormal retina vasculature morphology	J:282246
	decreased retina ganglion cell number	J:282246
	decreased total retina thickness	J:282246
	normal growth/size/body region phenotype	J:112029
	oxidative stress	J:282246
Igfbp3^tm1Lex/Igfbp3^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	abnormal basal metabolism	J:168345
	abnormal eating behavior	J:168345
	abnormal glucose homeostasis	J:168345
	decreased adiponectin level	J:168345
	decreased circulating triglyceride level	J:168345
	decreased white adipose tissue amount	J:168345
	increased body weight	J:168345
	increased circulating glucose level	J:168345
	increased circulating insulin level	J:168345
	increased liver weight	J:168345
	increased quadriceps weight	J:168345
	increased tibialis anterior weight	J:168345

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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