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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Igha
immunoglobulin heavy constant alpha
MGI:96444
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ighatm1(Myc)Janz/Igha+
involves: 129S1/Sv * C57BL/6 		increased B cell apoptosis J:90901
increased B cell derived lymphoma incidence J:90901
increased B cell proliferation J:90901
increased plasma cell number J:90901
Ighatm1(Myc)Janz/Igha+
Tg(Tnfsf13b)1Fma/0
involves: 129S1/Sv * C57BL/6 * DBA/2J 		enlarged spleen J:166158
increased B cell number J:166158
increased chronic lymphocytic leukemia incidence J:166158
increased lymphocyte cell number J:166158
increased mature B cell number J:166158
increased spleen white pulp amount J:166158
premature death J:166158
Ighatm1(Myc)Janz/Igha+
Tg(Igk-V21-Bax)1967Bvn/0
involves: 129S1/Sv * C57BL/6 * FVB/N 		abnormal B cell apoptosis J:90901
abnormal plasma cell morphology J:90901
decreased tumor-free survival time J:90901
enlarged spleen J:90901
increased IgG level J:90901
increased IgM level J:90901
increased leukemia incidence J:90901
increased plasma cell number J:90901
increased plasmacytoma incidence J:90901
Ighatm1Grh/Ighatm1Grh
Tg(Tnfsf13b)1Fma/Tg(Tnfsf13b)1Fma
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 		normal immune system phenotype J:178227
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory