Jchain Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Jchain
immunoglobulin joining chain
MGI:96493

9 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Jchain^tm1Jse/Jchain^tm1Jse C.129X1-Jchain^tm1Jse	decreased susceptibility to Herpesvirales infection	J:62298
	decreased susceptibility to Herpesvirales infection induced morbidity/mortality	J:62298
	increased susceptibility to parasitic infection	J:140515
Jchain^tm1Jse/Jchain^tm1Jse involves: 129X1/SvJ	abnormal B cell physiology	J:75843
	abnormal bile composition	J:75843
	abnormal intestinal secretion	J:34042, J:75843
	abnormal milk composition	J:34042
	increased IgA level	J:34042, J:75843
Jchain^tm2(Myc)Tl/Jchain^tm2(Myc)Tl involves: 129P2/OlaHsd * BALB/cJ * C57BL/6	abnormal humoral immune response	J:71355

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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