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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Igk-J
immunoglobulin kappa chain, joining region
MGI:96497
21 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Blnktm1Dkit/Blnktm1Dkit
Igh-Jtm1(3H9-VDJ)Mwg/Igh-J+
Igk-Jtm1Mwg/Igk-J+
involves: C57BL/6 * NZB 		abnormal immature B cell morphology J:94297
Igh-Jtm1.1Lave/Igh-Jtm1.1Lave
Igk-Jtm1.1Lave/Igk-Jtm1.1Lave
Not Specified 		abnormal B cell clonal deletion J:179317
abnormal B cell differentiation J:205708
abnormal B cell physiology J:205708
abnormal immunoglobulin level J:179317
arrested B cell differentiation J:179317, J:205708
decreased B cell number J:179317, J:205708
decreased immature B cell number J:205708
decreased mature B cell number J:205708
Igh-Jtm1.1Lave/Igh-Jtm1.1Lave
Igk-Jtm1.1Lave/Igk-Jtm1.1Lave
Tg(BCL2)22Wehi/0
involves: C57BL/6JWehi * SJL/JWehi 		abnormal B cell differentiation J:179317
Igh-Jtm1Dim/Igh-J+
Igk-Jtm1Dim/Igk-J+
involves: 129S4/SvJae * C57BL/6 		abnormal B cell differentiation J:107241
increased IgG level J:107241
increased IgM level J:107241
Igh-Jtm1Mcdl/Igh-Jtm1Mcdl
Igk-Jtm1Mcdl/Igk-Jtm1Mcdl
Rag1tm1Mom/Rag1tm1Mom
Tg(DO11.10)10Dlo/?
involves: 129S/Sv * BALB/c * C3H * C57BL/6 		abnormal spleen germinal center morphology J:100072
abnormal T cell differentiation J:100072
increased IgE level J:100072
increased IgG level J:100072
Igh-Jtm2.1(4E10)Lave/Igh-Jtm2.1(4E10)Lave
Igk-Jtm2.1(4E10)Lave/Igk-Jtm2.1(4E10)Lave
involves: C57BL/6 		abnormal B cell differentiation J:205708
abnormal B cell physiology J:205708
arrested B cell differentiation J:205708
decreased immature B cell number J:205708
decreased mature B cell number J:205708
Igk-Jtm1Cog/Igk-Jtm1.1Cog
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell number J:110100
abnormal plasma cell morphology J:110100
decreased B cell number J:110100
decreased naive B cell number J:110100
normal immune system phenotype J:110100
increased plasma cell number J:110100
increased pre-B cell number J:110100
Igk-Jtm1Cog/Igk-Jtm1Cog
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell physiology J:110100
decreased B cell number J:110100
Igk-Jtm1Mwg/Igktm1Dhu
involves: 129S7/SvEvBrd * C57BL/6 		normal immune system phenotype J:76116
Igk-Jtm2Mwg/Igktm1Dhu
involves: 129P2/OlaHsd * 129S7/SvEvBrd 		normal immune system phenotype J:76116
Igkctm1(IGKC)Mnz/Igkc+
Igk-Jtm1(CD4*)Mss/Igk-J+
involves: 129S4/SvJae 		abnormal immunoglobulin light chain V-J recombination J:143876
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory