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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ihh
Indian hedgehog
MGI:96533
24 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gli3Xt-J/Gli3Xt-J
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+
Ihhtm1Amc/Ihhtm1Amc
Tg(Col2a1-cre)3Amc/0
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ 		abnormal long bone diaphysis morphology J:154905
decreased body size J:154905
perinatal lethality, complete penetrance J:154905
short limbs J:154905
normal skeleton phenotype J:154905
Gli3Xt-J/Gli3Xt-J
Ihhtm1Amc/Ihhtm1Amc
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ 		abnormal bone marrow cavity morphology J:154905
abnormal perichondrium morphology J:154905
Gpc6tm1Lex/Gpc6+
Ihhtm1Amc/Ihh+
involves: 129S1/Sv * 129S5/SvEvBrd * 129X1/SvJ * C57BL/6N 		decreased fetal weight J:245694
short femur J:245694
Gpc6tm1Lex/Gpc6tm1Lex
Ihhtm1Amc/Ihhtm1Amc
involves: 129S1/Sv * 129S5/SvEvBrd * 129X1/SvJ * C57BL/6N 		decreased fetal weight J:245694
short femur J:245694
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+
Ihhtm1Amc/Ihhtm1Amc
involves: 129S1/Sv * 129X1/SvJ 		abnormal long bone epiphyseal plate proliferative zone J:154905
abnormal long bone hypertrophic chondrocyte zone J:154905
abnormal osteoblast differentiation J:154905
disorganized long bone epiphyseal plate J:154905
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+
Ihhtm1Amc/Ihhtm1Amc
Tg(Col2a1-cre)3Amc/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal long bone epiphyseal plate proliferative zone J:154905
abnormal long bone hypertrophic chondrocyte zone J:154905
abnormal osteoblast differentiation J:154905
abnormal perichondrium morphology J:154905
disorganized long bone epiphyseal plate J:154905
perinatal lethality, complete penetrance J:154905
normal skeleton phenotype J:154905
Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sortm3(Runx2)Flng
Ihhtm1Amc/Ihhtm1Amc
Tg(Col2a1-cre)3Amc/0
involves: 129S1/Sv * 129X1/SvJ 		abnormal bone ossification J:180304
abnormal bone structure J:180304
abnormal long bone epiphyseal plate morphology J:180304
abnormal long bone hypertrophic chondrocyte zone J:180304
abnormal osteoblast differentiation J:180304
Ihhtm1Amc/Ihh+
Pth1rtm1Hmk/Pth1rtm2Hmk
Tg(Bglap2-cre)1Kry/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB 		increased long bone epiphyseal plate size J:99641
Ihhtm1Amc/Ihhtm1Amc
Ptch1tm1Mps/Ptch1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal palatal shelf bone ossification J:182649
Ihhtm1Amc/Ihhtm1Amc
Shhtm1Amc/Shhtm1Amc
involves: 129/Sv * C57BL/6J * CBA/J 		embryonic growth arrest J:62158
Ihhtm1Amc/Ihhtm1Amc
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal visceral yolk sac mesenchyme morphology J:128367
abnormal visceral yolk sac morphology J:128367
absent vitelline blood vessels J:128367
failure of initiation of embryo turning J:128367
Ihhtm1Amc/Ihhtm2Amc
Pth1rtm1Hmk/Pth1rtm2Hmk
Tg(Bglap2-cre)1Kry/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB 		abnormal chondrocyte differentiation J:99641
Ihhtm2Amc/Ihh+
Pth1rtm1Hmk/Pth1rtm2Hmk
Tg(Bglap2-cre)1Kry/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 * FVB/N 		abnormal chondrocyte differentiation J:99641
abnormal long bone hypertrophic chondrocyte zone J:99641
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory