About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Il10ra
interleukin 10 receptor, alpha
MGI:96538
29 phenotypes from 6 alleles in 7 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Il10ratm1.1Jack/Il10ratm1.1Jack
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		normal immune system phenotype J:157787
Il10ram1Jskg/Il10ram1Jskg
B6.Cg-Il10ram1Jskg 		colitis J:146644
Il10raNZW/Il10ra+
(NZB x NZW)F1 		increased anti-chromatin antibody level J:102087
increased IgG level J:102087
Il10ratm1.1Jack/Il10ratm1.1Jack
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * BALB/c * C57BL/6 		abnormal chemokine level J:157787
abnormal cytokine level J:157787
increased circulating interferon-gamma level J:157787
increased circulating interleukin-1 alpha level J:157787
increased circulating interleukin-1 beta level J:157787
increased circulating interleukin-2 level J:157787
increased circulating interleukin-12 level J:157787
increased circulating interleukin-17 level J:157787
increased circulating tumor necrosis factor level J:157787
increased susceptibility to parasitic infection J:157787
Il10ratm1.1Jack/Il10ratm1.1Jack
Tg(Cd4-cre)1Cwi/0
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * DBA/2 		normal immune system phenotype J:157787
Il10ratm1.1Tlg/Il10ratm1.1Tlg
Tg(Cd4-cre)1Cwi/?
B6.Cg-Tg(Cd4-cre)1Cwi Il10ratm1.1Tlg 		abnormal lymphocyte cell number J:189797
abnormal regulatory T cell number J:189797
autoimmune response J:189797
decreased splenocyte proliferation J:189797
decreased T cell number J:189797
normal immune system phenotype J:189797
Il10ratm1.2Jack/Il10ratm1.2Jack
involves: 129P2/OlaHsd * BALB/c * C57BL/6 * DBA/2 		abnormal chemokine level J:157787
abnormal cytokine level J:157787
cecum inflammation J:157787
increased circulating interferon-gamma level J:157787
increased circulating interleukin-1 alpha level J:157787
increased circulating interleukin-1 beta level J:157787
increased circulating interleukin-2 level J:157787
increased circulating interleukin-6 level J:157787
increased circulating interleukin-12 level J:157787
increased circulating interleukin-17 level J:157787
increased circulating tumor necrosis factor level J:157787
increased susceptibility to induced colitis J:157787
increased susceptibility to parasitic infection J:157787
Il10ratm1b(KOMP)Wtsi/Il10ratm1b(KOMP)Wtsi
C57BL/6N-Il10ratm1b(KOMP)Wtsi/Orl 		abnormal auditory brainstem response J:211773
decreased blood urea nitrogen level J:211773
decreased lymphocyte cell number J:211773
decreased startle reflex J:211773
improved glucose tolerance J:211773
increased neutrophil cell number J:211773
Scn10atm2(cre)Jwo/Scn10a+
Il10ratm1.1Jack/Il10ratm1.1Jack
involves: 129P2/OlaHsd 		normal behavior/neurological phenotype J:326965
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory