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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Il12a
interleukin 12a
MGI:96539
13 phenotypes from 4 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Il12am1Btlr/Il12am1Btlr
C57BL/6J-Il12am1Btlr 		increased susceptibility to Herpesvirales infection J:267667
Il12atm1b(EUCOMM)Hmgu/Il12atm1b(EUCOMM)Hmgu
C57BL/6N-Il12atm1b(EUCOMM)Hmgu/H 		increased circulating HDL cholesterol level J:211773
vertebral fusion J:211773
Il12atm1Cab/Il12atm1Cab
B6.129S4-Il12atm1Cab 		abnormal NK cell physiology J:79552
decreased circulating interferon-gamma level J:79552
Il12atm1Cab/Il12atm1Cab
involves: 129S4/SvJae * C57BL/6 		decreased circulating interferon-gamma level J:54482
decreased circulating interleukin-12 level J:54482
Il12atm1Jm/Il12atm1Jm
129S1/Sv-Il12atm1Jm 		abnormal CD4-positive, alpha-beta T cell physiology J:34164
decreased susceptibility to type IV hypersensitivity reaction J:34164
increased susceptibility to parasitic infection J:34164
Il12atm1Jm/Il12atm1Jm
B6.129S1-Il12atm1Jm 		normal immune system phenotype J:120806
Il12atm1Jm/Il12atm1Jm
B6.129S1-Il12atm1Jm/J 		increased incidence of tumors by chemical induction J:111568
increased susceptibility to xenobiotic induced morbidity/mortality J:91927
Il12atm1Jm/Il12atm1Jm
C.129S1-Il12atm1Jm 		impaired natural killer cell mediated cytotoxicity J:125611
Il12atm1Jm/Il12atm1Jm
involves: 129S1/Sv 		abnormal NK cell physiology J:139001
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory