Il12a Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il12a
interleukin 12a
MGI:96539

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Il12a^tm1Cab/Il12a^tm1Cab Il23a^tm1.1Thak/Il23a^tm1.1Thak B6.Cg-Il12a^tm1Cab Il23a^tm1.1Thak	decreased susceptibility to experimental autoimmune encephalomyelitis	J:143970
Il12a^tm1Jm/Il12a^tm1Jm Il12b^tm1Jm/Il12b^tm1Jm B6.129S1-Il12a^tm1Jm Il12b^tm1Jm	impaired natural killer cell mediated cytotoxicity	J:125611
Il12a^tm1Jm/Il12a^tm1Jm Rag2^tm1Fwa/Rag2^tm1Fwa involves: 129S/SvEv * 129S1/Sv * 129S6/SvEvTac	abnormal interferon secretion	J:140483
	decreased susceptibility to bacterial infection	J:140483
	lung inflammation	J:140483

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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