Il13 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il13
interleukin 13
MGI:96541

31 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Chi3l1^tm1Eli/Chi3l1^tm1Eli Tg(Scgb1a1-rtTA,tetO-Il13)1Eli/0 involves: C57BL/6 * CBA	abnormal T-helper 2 cell number	J:148490
	abnormal T-helper 2 physiology	J:148490
Chit1^tm1Eli/Chit1^tm1Eli Tg(Scgb1a1-Il13)2Eli/0 involves: C57BL/6 * CBA	decreased susceptibility to bacterial infection	J:189872
Gata3^tm1Iho/Gata3^tm1Iho Il13^{tm1(YFP/cre)Lky}/Il13⁺ involves: 129S4/SvJae	decreased eosinophil cell number	J:178986
	increased susceptibility to parasitic infection	J:178986
Gt(ROSA)26Sor^tm1(DTA)Lky/Gt(ROSA)26Sor⁺ Il13^{tm1(YFP/cre)Lky}/Il13^{tm1(YFP/cre)Lky} involves: 129P2/OlaHsd * 129S4/SvJae	decreased eosinophil cell number	J:178986
	decreased IgG1 level	J:178986
	decreased interleukin-5 secretion	J:178986
	decreased interleukin-13 secretion	J:178986
	increased susceptibility to parasitic infection	J:178986
Il4/Il13^tm1.1Lky/Il4/Il13^tm1.1Lky Il4/Il13^tm1.1Lky/Il4/Il13^tm1.1Lky involves: 129P2/OlaHsd * BALB/c	decreased core body temperature	J:178294
	decreased fatty acids level	J:178294
	decreased noradrenaline level	J:178294
	increased susceptibility to weight loss	J:178294
Il4ra^tm2Tch/Il4ra^tm2Tch Tg(Scgb1a1-rtTA,tetO-Il13)1Eli/? B6.Cg-Il4ra^tm2Tch Tg(Scgb1a1-rtTA,tetO-IL13)1Eli	increased eosinophil cell number	J:152376
	increased respiratory mucosa goblet cell number	J:152376
	respiratory system inflammation	J:152376
Il13^{tm1(YFP/cre)Lky}/Il13⁺ Il4^tm1(CD2)Mmrs/Il4⁺ Gt(ROSA)26Sor^tm1(DTA)Lky/Gt(ROSA)26Sor⁺ involves: 129P2/OlaHsd * 129S4/SvJae	decreased eosinophil cell number	J:178986
	increased susceptibility to parasitic infection	J:178986
Il13^tm1.1Anjm/Il13^tm1.1Anjm Tg(DO11.10)10Dlo/0 involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6	abnormal CD4-positive, alpha-beta T cell physiology	J:91403
	decreased interleukin-13 secretion	J:91403
Il13^tm1Anjm/Il13⁺ Il4^tm1.1Wep/Il4⁺ involves: 129P2/OlaHsd * BALB/c * C57BL/6	decreased interleukin-4 secretion	J:69099
Il13^tm1Anjm/Il13^tm1Anjm Il5^tm3Anjm/Il5^tm3Anjm involves: 129P2/OlaHsd * C57BL/6	granulomatous inflammation	J:113543
	increased susceptibility to parasitic infection	J:113543
Il13^tm2Anjm/Il13^tm2Anjm Tg(SFTPC-Il18)AThos/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * DBA/2	abnormal pulmonary alveolus morphology	J:147547
	decreased skeletal muscle weight	J:219136
	normal skeleton phenotype	J:219136
	weight loss	J:219136
Il13^tm3.1Anjm/Il13⁺ Il1rl1^tm1Anjm/Il1rl1^tm1Anjm involves: 129P2/OlaHsd * BALB/c	decreased eosinophil cell number	J:159464
Il13^tm3.1Anjm/Il13⁺ Il17rb^tm1Anjm/Il17rb^tm1Anjm involves: BALB/c * C57BL/6	decreased eosinophil cell number	J:159464
Il13^tm3.1Anjm/Il13⁺ Il17rb^tm1Anjm/Il17rb^tm1Anjm Il1rl1^tm1Anjm/Il1rl1^tm1Anjm involves: 129P2/OlaHsd * BALB/c	decreased eosinophil cell number	J:159464
Stat6^tm1Gru/Stat6⁺ Tg(Scgb1a1-Il13)2Eli/? involves: 129S2/SvPas * C57BL/6 * CBA	abnormal lung morphology	J:132385
	abnormal lung size	J:132385
	abnormal pulmonary alveolus morphology	J:132385
	abnormal respiratory system morphology	J:132385
	abnormal respiratory system physiology	J:132385
	overexpanded pulmonary alveolus	J:132385
	respiratory system inflammation	J:132385
Stat6^tm1Gru/Stat6^tm1Gru Tg(Scgb1a1-Il13)2Eli/? involves: 129S2/SvPas * C57BL/6 * CBA	normal respiratory system phenotype	J:132385
Stat6^tm1Gru/Stat6^tm1Gru Tg(Scgb1a1-Il13)2Eli/? Tg(Scgb1a1-STAT6)1Erle/? involves: 129S2/SvPas * C57BL/6 * CBA * FVB	abnormal respiratory system physiology	J:132385
	normal respiratory system phenotype	J:132385
Tmem219^{tm1(KOMP)Vlcg}/Tmem219^{tm1(KOMP)Vlcg} Tg(Scgb1a1-rtTA,tetO-Il13)1Eli/0 involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA	increased transforming growth factor beta level	J:236976
	lung inflammation	J:236976
	pulmonary fibrosis	J:236976

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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